MethBase is a database of DNA methylation data derived from next-generation sequencing data.[1] MethBase provides a visualization of publicly available bisulfite sequencing and reduced representation bisulfite sequencing experiments through the UCSC Genome Browser. MethBase contents include single-CpG site resolution methylation levels for each CpG site in the genome of interest, annotation of regions of hypomethylation often associated with gene promoters, and annotation of allele-specific methylation associated with genomic imprinting.

MethBase
Content
DescriptionDatabase for single cytosine resolution DNA methylation data and associated annotations.
OrganismsHuman
Chimpanzee
Gorilla
Rhesus Macaque
Mouse
Arabidopsis
Contact
LaboratoryAndrew D. Smith
Primary citationQiang Song et al. (2013) [1]
Release date2013
Access
Data formatTrackhub on the UCSC Genome Browser
Websitehttp://smithlabresearch.org/software/methbase/

See also

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References

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  1. ^ a b Song, Qiang; Decato Benjamin E; Hong Elizabeth; Zhou Meng; Fang Fang; Qu Jianghan; Garvin Tyler; Kessler Michael; Zhou Jun; Smith Andrew D (Dec 2013). "A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics". PLOS ONE. 8 (12): e81148. Bibcode:2013PLoSO...881148S. doi:10.1371/journal.pone.0081148. PMC 3855694. PMID 24324667.
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