Myosin light chain 6B is a protein that in humans is encoded by the MYL6B gene.[5][6][7] Myosin is a hexameric ATPase cellular motor protein. It is composed of two heavy chains, two nonphosphorylatable alkali light chains, and two phosphorylatable regulatory light chains. This gene encodes a myosin alkali light chain expressed in both slow-twitch skeletal muscle and in nonmuscle tissue.[7]

MYL6B
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesMYL6B, MLC1SA, myosin light chain 6B
External IDsOMIM: 609930; MGI: 1917789; HomoloGene: 86887; GeneCards: MYL6B; OMA:MYL6B - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_002475
NM_001199629

NM_172259

RefSeq (protein)

NP_001186558
NP_002466

NP_758463

Location (UCSC)Chr 12: 56.15 – 56.16 MbChr 10: 128.33 – 128.33 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000196465Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000039824Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Zimmermann K, Starzinski-Powitz A (Feb 1990). "A novel isoform of myosin alkali light chain isolated from human muscle cells". Nucleic Acids Res. 17 (24): 10496. doi:10.1093/nar/17.24.10496. PMC 335321. PMID 2602161.
  6. ^ Hailstones DL, Gunning PW (Mar 1990). "Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function". Mol Cell Biol. 10 (3): 1095–104. doi:10.1128/mcb.10.3.1095. PMC 360973. PMID 2304459.
  7. ^ a b "Entrez Gene: MYL6B myosin, light chain 6B, alkali, smooth muscle and non-muscle".

Further reading

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  • Overview of all the structural information available in the PDB for UniProt: P14649 (Human Myosin light chain 6B (MYL6B)) at the PDBe-KB.