Hepatitis B virus PRE beta

The Hepatitis B virus PRE stem-loop beta (HBV PRE SL-beta) is an RNA structure that is shown to play a role in nuclear export of HBV mRNAs.

Hepatitis B virus PRE beta
Identifiers
SymbolHBV_PREbeta
RfamHBV_PREbeta
Other data
RNA typeCis-reg;
PDB structuresPDBe

The minimal HBV PREbeta structure consists of a 23 nt stem-loop, with a 9 nt apical loop. The conserved stem-loop was predicted within the HBV PRE sequence and confirmed by mutagenesis.[1][2]

See also

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References

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  1. ^ Smith Gj, 3rd; Donello, JE; Lück, R; Steger, G; Hope, TJ (1998). "The hepatitis B virus post-transcriptional regulatory element contains two conserved RNA stem-loops which are required for function". Nucleic Acids Research. 26 (21): 4818–4827. doi:10.1093/nar/26.21.4818. PMC 147918. PMID 9776740.{{cite journal}}: CS1 maint: numeric names: authors list (link)
  2. ^ Chen, A; Panjaworayan T-Thienprasert, N; Brown, CM (7 July 2014). "Prospects for inhibiting the post-transcriptional regulation of gene expression in hepatitis B virus". World Journal of Gastroenterology. 20 (25): 7993–8004. doi:10.3748/wjg.v20.i25.7993. PMC 4081668. PMID 25009369.