Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 is a protein that in humans is encoded by the GNG2 gene.[5][6]

GNG2
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesGNG2, G protein subunit gamma 2
External IDsOMIM: 606981; MGI: 102705; HomoloGene: 40715; GeneCards: GNG2; OMA:GNG2 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001243773
NM_001243774
NM_053064

RefSeq (protein)

NP_001230702
NP_001230703
NP_444292

Location (UCSC)Chr 14: 51.83 – 51.98 MbChr 14: 19.92 – 20.03 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Heterotrimeric G proteins play vital roles in cellular responses to external signals. The specificity of a G protein-receptor interaction is primarily mediated by the gamma subunit.[supplied by OMIM][6]

Interactive pathway map

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Click on genes, proteins and metabolites below to link to respective articles.[§ 1]

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|alt=Nicotine Activity on Dopaminergic Neurons edit]]
Nicotine Activity on Dopaminergic Neurons edit
  1. ^ The interactive pathway map can be edited at WikiPathways: "NicotineDopaminergic_WP1602".

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000186469Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000043004Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Modarressi MH, Taylor KE, Wolfe J (Jul 2000). "Cloning, characterization, and mapping of the gene encoding the human G protein gamma 2 subunit". Biochem Biophys Res Commun. 272 (2): 610–5. doi:10.1006/bbrc.2000.2832. PMID 10833460.
  6. ^ a b "Entrez Gene: GNG2 guanine nucleotide binding protein (G protein), gamma 2".

Further reading

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