E2F-associated phosphoprotein is a protein that in humans is encoded by the EAPP gene.[5][6]

EAPP
Identifiers
AliasesEAPP, BM036, C14orf11, E2F associated phosphoprotein
External IDsOMIM: 609486; MGI: 1913516; HomoloGene: 10206; GeneCards: EAPP; OMA:EAPP - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_018453
NM_001318916

NM_025456
NM_001331162

RefSeq (protein)

NP_001305845
NP_060923

NP_001318091
NP_079732

Location (UCSC)Chr 14: 34.52 – 34.54 MbChr 12: 54.72 – 54.74 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

This gene encodes a phosphoprotein that interacts with several members of the E2F family of proteins. The protein localizes to the nucleus, and is present throughout the cell cycle except during mitosis. It functions to modulate E2F-regulated transcription and stimulate proliferation.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000129518Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000054302Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Novy M, Pohn R, Andorfer P, Novy-Weiland T, Galos B, Schwarzmayr L, Rotheneder H (Apr 2005). "EAPP, a novel E2F binding protein that modulates E2F-dependent transcription". Mol Biol Cell. 16 (5): 2181–90. doi:10.1091/mbc.E04-11-0975. PMC 1087227. PMID 15716352.
  6. ^ a b "Entrez Gene: C14orf11 chromosome 14 open reading frame 11".

Further reading

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