Dinovernavirus is a genus of double-stranded RNA viruses in the family Reoviridae and subfamily Spinareovirinae. Member viruses replicate in a variety of mosquito cell lines. The name is an abbreviation for double-stranded, insect, novem (Latin for nine the number of genome segments), rna virus. There is one species in the genus: Aedes pseudoscutellaris reovirus.[1][2]

Dinovernavirus
Cryo-EM reconstruction of Fako virus capsid showing: turret protein (red), clamp protein (yellow), and homodimer of major capsid protein (blue/purple)
Virus classification Edit this classification
(unranked): Virus
Realm: Riboviria
Kingdom: Orthornavirae
Phylum: Duplornaviricota
Class: Resentoviricetes
Order: Reovirales
Family: Sedoreoviridae
Subfamily: Spinareovirinae
Genus: Dinovernavirus

Structure

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Viruses in Dinovernavirus are non-enveloped. Their capsid is turreted and single shelled with icosahedral geometries and T=2 symmetry. The diameter is around 49–50 nm.[1]

Genome

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Genomes are linear and segmented. There are nine segments which code for nine proteins.[1]

Life cycle

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Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. The virus exits the host cell by monopartite non-tubule guided viral movement. Mosquito serve as the natural host.[1]

Taxonomy

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There is one species in the genus:[2]

  • Aedes pseudoscutellaris reovirus

References

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  1. ^ a b c d "Viral Zone". ExPASy. Retrieved 13 August 2015.
  2. ^ a b "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 13 May 2021.
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