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Cellular nucleic acid-binding protein is a protein that in humans is encoded by the CNBP gene.[5][6][7]

CNBP
Identifiers
AliasesCNBP, CNBP1, DM2, PROMM, RNF163, ZCCHC22, ZNF9, CCHC-type zinc finger nucleic acid binding protein
External IDsMGI: 88431 HomoloGene: 2567 GeneCards: CNBP
Gene location (Human)
Chromosome 3 (human)
Chr.Chromosome 3 (human)[1]
Chromosome 3 (human)
Genomic location for CNBP
Genomic location for CNBP
Band3q21.3Start129,169,484 bp[1]
End129,183,922 bp[1]
RNA expression pattern
PBB GE CNBP 206158 s at fs.png
More reference expression data
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001109745
NM_001109746
NM_013493
NM_001347325
NM_001355195

RefSeq (protein)

NP_001103215
NP_001103216
NP_001334254
NP_038521
NP_001342124

Location (UCSC)Chr 3: 129.17 – 129.18 MbChr 6: 87.84 – 87.85 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Contents

FunctionEdit

The ZNF9 protein contains 7 zinc finger domains and is believed to function as an RNA-binding protein. A CCTG expansion in intron 1 of the ZNF9 gene results in myotonic dystrophy type 2 (MIM 602668).[supplied by OMIM][7]

ReferencesEdit

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000169714 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000030057 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". 
  4. ^ "Mouse PubMed Reference:". 
  5. ^ Lusis AJ, Rajavashisth TB, Klisak I, Heinzmann C, Mohandas T, Sparkes RS (Oct 1990). "Mapping of the gene for CNBP, a finger protein, to human chromosome 3q13.3-q24". Genomics. 8 (2): 411–4. doi:10.1016/0888-7543(90)90303-C. PMID 2249857. 
  6. ^ Liquori CL, Ricker K, Moseley ML, Jacobsen JF, Kress W, Naylor SL, Day JW, Ranum LP (Aug 2001). "Myotonic dystrophy type 2 caused by a CCTG expansion in intron 1 of ZNF9". Science. 293 (5531): 864–7. doi:10.1126/science.1062125. PMID 11486088. 
  7. ^ a b "Entrez Gene: CNBP CCHC-type zinc finger, nucleic acid binding protein". 

Further readingEdit

External linksEdit

This article incorporates text from the United States National Library of Medicine, which is in the public domain.