ZDHHC9

Palmitoyltransferase ZDHHC9 is an enzyme that in humans is encoded by the ZDHHC9 gene that contains a DHHC domain.

ZDHHC9
Identifiers
Aliases	ZDHHC9, CGI89, CXorf11, DHHC9, MMSA1, MRXSZ, ZDHHC10, ZNF379, ZNF380, zinc finger DHHC-type containing 9, zinc finger DHHC-type palmitoyltransferase 9, MRXSR
External IDs	OMIM: 300646 MGI: 2444393 HomoloGene: 91149 GeneCards: ZDHHC9
Gene location (Human) Chr. X chromosome (human) Band Xq26.1 Start 129,803,288 bp End 129,843,909 bp
Gene location (Mouse) Chr. X chromosome (mouse) Band X|X A4 Start 47,260,846 bp End 47,297,755 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in corpus callosum inferior ganglion of vagus nerve external globus pallidus subthalamic nucleus internal globus pallidus ventral tegmental area pons medulla oblongata stromal cell of endometrium Brodmann area 46 Top expressed in esophagus lip left lobe of liver ileum intestinal villus crypt of lieberkuhn of small intestine yolk sac ankle joint fossa corneal stroma More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-cysteine S-palmitoyltransferase activity Ras palmitoyltransferase activity transferase activity acyltransferase activity protein binding palmitoyltransferase activity Cellular component integral component of membrane palmitoyltransferase complex Golgi membrane Golgi apparatus intrinsic component of Golgi membrane endoplasmic reticulum membrane endoplasmic reticulum membrane cytosol Biological process peptidyl-L-cysteine S-palmitoylation protein palmitoylation protein targeting to membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 51114 208884 Ensembl ENSG00000188706 ENSMUSG00000036985 UniProt Q9Y397 P59268 RefSeq (mRNA) NM_001008222 NM_016032 NM_172465 RefSeq (protein) NP_001008223 NP_057116 NP_766053 Location (UCSC) Chr X: 129.8 – 129.84 Mb Chr X: 47.26 – 47.3 Mb PubMed search
Wikidata
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Further reading

• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Clark HF, Gurney AL, Abaya E, et al. (2003). "The Secreted Protein Discovery Initiative (SPDI), a Large-Scale Effort to Identify Novel Human Secreted and Transmembrane Proteins: A Bioinformatics Assessment". Genome Res. 13 (10): 2265–70. doi:10.1101/gr.1293003. PMC 403697. PMID 12975309.
• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
• Fu GK, Wang JT, Yang J, et al. (2005). "Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes". Genomics. 84 (1): 205–10. doi:10.1016/j.ygeno.2004.01.011. PMID 15203218.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–27. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
• Swarthout JT, Lobo S, Farh L, et al. (2005). "DHHC9 and GCP16 constitute a human protein fatty acyltransferase with specificity for H- and N-Ras". J. Biol. Chem. 280 (35): 31141–48. doi:10.1074/jbc.M504113200. PMID 16000296.
• Raymond FL, Tarpey PS, Edkins S, et al. (2007). "Mutations in ZDHHC9, Which Encodes a Palmitoyltransferase of NRAS and HRAS, Cause X-Linked Mental Retardation Associated with a Marfanoid Habitus". Am. J. Hum. Genet. 80 (5): 982–87. doi:10.1086/513609. PMC 1852737. PMID 17436253.
• Mansilla F, Birkenkamp-Demtroder K, Kruhøffer M, et al. (2007). "Differential expression of DHHC9 in microsatellite stable and instable human colorectal cancer subgroups". Br. J. Cancer. 96 (12): 1896–903. doi:10.1038/sj.bjc.6603818. PMC 2359975. PMID 17519897.