Viral structural protein

A viral structural protein is a viral protein that is a structural component of the mature virus.[1]

Examples include the SARS coronavirus 3a and 7a accessory proteins.[2][3]

Bacteriophage T4 structural proteins


During assembly of the bacteriophage (phage) T4 virion, the structural proteins encoded by the phage genes interact with each other in a characteristic sequence. Maintaining an appropriate balance in the amounts of each of these structural proteins produced during viral infection appears to be critical for normal phage T4 morphogenesis.[4] Phage T4 encoded proteins that determine virion structure include major structural components, minor structural components and non-structural proteins that catalyze specific steps in the morphogenesis sequence.[5] Phage T4 morphogenesis is divided into three independent pathways: the head, the tail and the long tail fibres as detailed by Yap and Rossman.[6]

See also



  1. ^ Viral+Structural+Proteins at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
  2. ^ Ito N, Mossel EC, Narayanan K, et al. (March 2005). "Severe acute respiratory syndrome coronavirus 3a protein is a viral structural protein". J. Virol. 79 (5): 3182–6. doi:10.1128/JVI.79.5.3182-3186.2005. PMC 548460. PMID 15709039.
  3. ^ Huang C, Ito N, Tseng CT, Makino S (August 2006). "Severe acute respiratory syndrome coronavirus 7a accessory protein is a viral structural protein". J. Virol. 80 (15): 7287–94. doi:10.1128/JVI.00414-06. PMC 1563709. PMID 16840309.
  4. ^ Floor E. Interaction of morphogenetic genes of bacteriophage T4. J Mol Biol. 1970;47(3):293-306. doi:10.1016/0022-2836(70)90303-7
  5. ^ Snustad DP. Dominance interactions in Escherichia coli cells mixedly infected with bacteriophage T4D wild-type and amber mutants and their possible implications as to type of gene-product function: catalytic vs. stoichiometric. Virology. 1968;35(4):550-563. doi:10.1016/0042-6822(68)90285-7
  6. ^ Yap ML, Rossmann MG. Structure and function of bacteriophage T4. Future Microbiol. 2014;9(12):1319-1327. doi:10.2217/fmb.14.91