Varzob District (Tajik: Ноҳияи Варзоб, translit. Nohiyayi Varzob) is a district in the Region of Republican Subordination in Tajikistan, lying north of Dushanbe. It borders on Hisor District from the west, Rudaki District from the south, and Vahdat District from the east. The Gissar Range runs along its northern edge. The Varzob River traverses the entire district north to south. The district capital is Varzob.