The Upsala Glacier is a large valley glacier on the eastern side of the Southern Patagonian Ice Field. Its higher portion lies in a disputed territory between Chile and Argentina. While the glacier flows from north to south it has three lesser eastflowing tributary glacier: Bertacchi, Cono and Murallón.
The glacier terminus is at Upsala channel of Lago Argentino. The Upsala Glacier is well known for its rapid retreat, which many see as evidence for global warming. Its retreat has been ongoing since the glacier was first documented in 1810. 
The glacier showed almost continual recession up until 1999. The acceleration in ice motion during the two decades preceding 1999 may have been augmented by the release of backstress when the glacier retreated beyond the islands in Brazo Upsala. Another period of even faster retreat started in 2008.
As of 2018 Upsala Glacier has retreated to such degree that it no longer constrain its tributary Bertacchi Glacier. Likely this makes Bertacchi Glacier have higher flow rates reflected with a subsequent stretching and thinning out of parts of the glacier as well. At parts the velocity of flow is also thought to have increased in Bertacchi Glacier as result of the near-separation from Upsala Glacier.
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- Moragues, Silvana; Lenzano, M. Gabriela; Lo Vecchio, Andrés; Falaschi, Daniel; Lenzano, Luis (2018). "Surface velocities of Upsala glacier, Southern Patagonian Andes, estimated using cross-correlation satellite imagery: 2013-2014 period". Andean Geology. 45 (1): 87–103. doi:10.5027/andgeoV45n1-3034. Retrieved February 10, 2018.
- "Glaciar Upsala en el año 1928" Greenpeace Argentina
- "Un glaciar patagónico se redujo 13,4 km2 en los últimos 7 años" - Clarín
- South Patagonian Icefield at NASA Earth Observatory, June 28, 2017]
- Peru For Less- Destinations- Argentina- Calafate- Perito Moreno Glacier, Upsala Glacier, el Torre Glacier, and El Chalten
- Skvarca, Pedro; Raup, Bruce; De Angelis, Hernán (2003). "Recent behaviour of Glaciar Upsala, a fast-flowing calving glacier in Lago Argentino, southern Patagonia" (PDF). Annals of Glaciology. 36 (1): 184–188. doi:10.3189/172756403781816202.
- Sakakibara, Daiki; Sugiyama, Shin; Sawagaki, Takanobu; Marinsek, Sebastián; Skvarca, Pedro (2013). "Rapid retreat, acceleration and thinning of Glaciar Upsala, Southern Patagonia Icefield, initiated in 2008" (PDF). Annals of Glaciology. 54 (63): 131–138. doi:10.3189/2013AoG63A236.