Tribulus terrestris (Malayalam: ഞെരിഞ്ഞിൽ) is an annual plant in the caltrop family (Zygophyllaceae) widely distributed around the world, that is adapted to grow in dry climate locations in which few other plants can survive.
|Leaves and flower|
It is an invasive species in North America. Like many weedy species, this plant has many common names, including goat's-head, bindii, bullhead, burra gokharu, bhakhdi, caltrop, small caltrops, cat's-head, devil's eyelashes, devil's-thorn, devil's-weed, puncture vine, puncturevine, and tackweed.
Habitat and rangeEdit
A network of fine rootlets arise from the taproot to take advantage of soil moisture, by which the plant can survive in very arid conditions.
The stems radiate from the crown to a diameter of about 10 cm (3.9 in) to over 1 m (3 ft 3 in), often branching. They are usually prostrate, forming flat patches, though they may grow more upwards in shade or among taller plants.
Leaves and stemEdit
The flowers are 4–10 mm (0.16–0.39 in) wide, with five lemon-yellow petals, five sepals, and ten stamens. In Southern California, it blooms from April through October, where it is highly invasive in waste places and disturbed sites.
The nutlets are hard and bear two to four sharp spines, 10 mm (0.39 in) long and 4–6 mm (0.16–0.24 in) broad point-to-point. These nutlets strikingly resemble goats' or bulls' heads; the "horns" are sharp enough to puncture bicycle tires and lawn mower tires. They can also cause painful injury to bare feet; however, they are also large enough to pull out as soon as they pierce into the sole, and the resultant hole is only slightly larger than stepping on a push pin if it goes all the way in.
Within each nutlet, seeds are stacked on top of each other, separated by a hard membrane. As an adaptation to dry climates, the largest seed germinates first, while the others may wait until more moisture is available before germinating.
The Greek word, τρίβολος meaning 'water-chestnut', translated into Latin as tribulos. The Latin name tribulus originally meant the caltrop (a spiky weapon), but in Classical times already the word meant this plant as well.
Cultivation and usesEdit
The plant is widely naturalized in the Americas and also in Australia south of its native range. In some states in the United States, it is considered a noxious weed and an invasive species. It is a declared plant in South Australia.
In Siddha medicine, Tribulus terrestris is known in Tamil as Nerunjil, yanai vanangi, thirikandam, siru nerunjil. This whole plant is used in the form of decoction to treat urinary tract infections, urolithiasis, dysmenorrhea, edema.
In Ayurvedic pharmacology, tribulus terrestris is used as a powder form of the aerial parts, particularly the fruits, and it is known in Sanskrit as gokshura, meaning the "cow's hoof", possibly because the small thorns tend to get stuck on grazing animals. Nevertheless, an unrelated plant, pedalium is also known as gokshura, more specifically as bada gokshura ("big cow's hoof"), whereas the gokshura proper is referred to as chhota gokshura ("small cow's hoof"). The two herbs are often found mixed in powder blends used.
Gokshura is believed to contribute to overall physical, as well as sexual, strength by building all the tissues, especially shukra dhatu (reproductive tissue) but it is not considered as a particular vajikarana (sexual functions) herb. It is believed to be useful in kidney, bladder, urinary tract and uro-genital related conditions, where it is said to act as a diuretic.
Tribulus terrestris is used in Unani under the Urdu name Khar-e-Khasak Khurd and the pedalium is referred to as Khar-e-Khasak Kalan. Their administration and indications are essentially similar with Ayurveda.
Tribulus terrestris is called Mitser Kaend (kund singular) in Kashmiri. They are used as a diuretic. A tea made out of them is given to treat fevers of all kinds.
Traditional Chinese medicineEdit
In traditional Chinese medicine Tribulus terrestris is known under the name bai ji li (白蒺藜). Tribulus terrestris known as ci ji li (刺蒺藜). "Confusion with Astragali complanati Semen (sha yuan zi) originally known as white ji li (白蒺藜 bai ji li), led some writers to attribute tonifying properties to this herb ..."
Some body builders use T. terrestris extract as a dietary supplement with the belief that it increases testosterone levels. The belief was popularized by the American bodybuilder Jeffrey Petermann in the early 1970s. However, T. terrestris has failed to increase testosterone levels in controlled studies. It has also failed to demonstrate strength-enhancing properties, a finding indicating that the purported anabolic steroid effects of Tribulus terrestris are untrue.
At the same time a scientific research based on World Health organization criteria (published in Cryobiology magazine, 2017-Apr) showed: the protective effects of Tribulus terrestris, which improves human sperm motility and viability, may be due to its antioxidant properties. On the basis of the results, the researchers concluded that Tribulus terrestris can be used as a safe therapeutic alternative to current modalities for the management of motility dysfunction in males.
A single study has shown that T. terrestris can alter sexual behavior in castrated rats. It appears to do so by stimulating androgen receptors in the brain. A research review conducted in 2000 stated that the lack of data outside of this study prevents generalizing the results to humans, particularly healthy individuals.
Animal studies in rats, rabbits, and primates have demonstrated ambiguous results. One study found that administration of Tribulus terrestris extract can produce statistically significant increases in levels of testosterone, dihydrotestosterone, and dehydroepiandrosterone, and produces effects suggestive of aphrodisiac activity.
A recent study found that T. terrestris caused no increase in testosterone or LH in young men, and another found that a commercial supplement containing androstenedione and herbal extracts including T. terrestris, was no more effective at raising testosterone levels than androstenedione alone.
A small research study of 67 women was published in 2014, finding "Tribulus terrestris may safely and effectively improve desire in women with hypoactive sexual desire disorder."
This section needs additional citations for verification. (June 2014) (Learn how and when to remove this template message)
Where this is a non-indigenous species, eradication methods are often sought. There are both biological and herbicidal solutions to the problem, but none of them provide a solution that is both quick and long-lasting, because T. terrestris seeds remain viable for up to seven years on average.
In smaller areas, T. terrestris is best controlled with manual removal, using a hoe to cut the plant off at its taproot. While this is effective, removing the entire plant by gripping the taproot, stem or trunk and pulling upward to remove the taproot is far more effective. This requires monitoring the area and removing the weed throughout the preseeding time (late spring and early summer in many temperate areas). This will greatly reduce the prevalence of the weed the following year. Mowing is not an effective method of eradication, because the plant grows flat against the ground.
Another avenue of physical eradication is to crowd out the opportunistic weed by providing good competition from favorable plants. Aerating compacted sites and planting competitive desirable plants, including broad-leaved grasses such as St. Augustine, can reduce the effect of T. terrestris by reducing resources available to the weed.
Chemical control is generally recommended for home control of T. terrestris. There are few pre-emergent herbicides that are effective. Products containing oryzalin, benefin, or trifluralin will provide partial control of germinating seeds. These must be applied prior to germination (late winter to midspring).
After plants have emerged from the soil (postemergent), products containing 2,4-dichlorophenoxyacetic acid (2,4-D), glyphosate, and dicamba are effective on T. terrestris. Like most postemergents, they are more effectively maintained when caught small and young. Dicamba and 2,4-D will cause harm to most broad-leaved plants, so the user should take care to avoid over-application. They can be applied to lawns without injuring the desired grass. Glyphosate will kill or injure most plants, so it should only be used as a spot treatment or on solid stands of the weed. A product from DuPont called Pastora is highly effective but expensive and not for lawn use.
Two weevils, Microlarinus lareynii and M. lypriformis, native to India, France, and Italy, were introduced into the United States as biocontrol agents in 1961. Both species of weevils are available for purchase from biological suppliers, but purchase and release is not often recommended because weevils collected from other areas may not survive at the purchaser's location.
Microlarinus lareynii is a seed weevil that deposits its eggs in the young burr or flower bud. The larvae feed on and destroy the seeds before they pupate, emerge, disperse, and start the cycle over again. Its life cycle time is 19 to 24 days. Microlarinus lypriformis is a stem weevil that has a similar life cycle, excepting the location of the eggs, which includes the undersides of stems, branches, and the root crown. The larvae tunnel in the pith where they feed and pupate. Adults of both species overwinter in plant debris. Although the stem weevil is slightly more effective than the seed weevil when each is used alone, the weevils are most effective if used together and the T. terrestris plant is moisture-stressed.
Research shows that the phytochemistry of T. terrestris samples collected from various parts of the world differs significantly. Among the steroidal saponins present in this herb, furostanol saponins are isolated only from T. terrestris of Bulgarian origin. One of the main chemical compounds found in T. terrestris is protodioscin (PTN). Also, T. terrestris was shown to have strong inhibitory activity on COX-2.
Two alkaloids that seem to cause limb paresis (staggers) in sheep that eat Tribulus terrestulis are the beta-carboline alkaloids harman (harmane) and norharman (norharmane). The alkaloid content of dried foliage is about 44 mg/kg.
- "Tribulus terrestris". Germplasm Resources Information Network (GRIN). Agricultural Research Service (ARS), United States Department of Agriculture (USDA). Retrieved 2008-03-18.
- Flowering Plants of the Santa Monica Mountains, Nancy Dale, 2nd Ed., 2000, p. 200
- "Caltrop - Tribulus terrestris". Weeds Australia. National Weeds Management Facilitator. Retrieved 2009-03-10.
- ഞെരിഞ്ഞിൽ "BSBI List 2007". Botanical Society of Britain and Ireland. Archived from the original (xls) on 2015-01-25. Retrieved 2014-10-17.
- Hyde, M.A. & Wursten, B. (2011). Flora of Mozambique
- "Tribulus terrestris". Natural Resources Conservation Service PLANTS Database. USDA. Retrieved 3 February 2016.
- North Dakota Department of Agriculture (n.d.). "Puncturevine (Tribulus terrestris)" (PDF). Retrieved 2 Sep 2011.
- "Zygophyllaceae" (PDF). Council of Heads of Australasian Herbaria. Retrieved 2010-03-13.
- Tribulus terrestris in BoDD – Botanical Dermatology Database
- "Greek Word Study Tool: τρίβολος". perseus.tufts.edu. Retrieved 11 August 2012.
- Charlton T. Lewis, Charles Short, A Latin Dictionary
- Dept. of Primary Industry and Regions > Biosecurity > Weeds and pest animals > Plant pests in South Australia > Plant policies Accessed 14 April 2015.
- Kevalia J, Patel B (2011). "Identification of fruits of Tribulus terrestris Linn. and Pedalium murex Linn.: A pharmacognostical approach". Ayu. 32 (4): 550–3. doi:10.4103/0974-8520.96132. PMC 3361934. PMID 22661853.
- "Gokshura - Ayurveda Glossary". Ayurveda Glossary. Retrieved 2017-07-17.
- National R & D Facility for Rasayana
- Bensky and Clavey (2004). Materia medica (3rd ed.). pp. 975–976.CS1 maint: Uses authors parameter (link)
- Brown GA, Vukovich MD, Reifenrath TA, Uhl NL, Parsons KA, Sharp RL, King DS (2000). "Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men". International Journal of Sport Nutrition and Exercise Metabolism. 10 (3): 340–59. PMID 10997957.
- Brown GA, Vukovich MD, Martini ER, Kohut ML, Franke WD, Jackson DA, King DS (2001). "Endocrine and lipid responses to chronic androstenediol-herbal supplementation in 30 to 58 year old men". J Am Coll Nutr. 20 (5): 520–8. doi:10.1080/07315724.2001.10719061. PMID 11601567.
- Neychev VK, Mitev VI (2005). "The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men". Journal of Ethnopharmacology. 101 (1–3): 319–23. doi:10.1016/j.jep.2005.05.017. PMID 15994038.
- Rogerson, S.; Riches, C. J.; Jennings, C.; Weatherby, R. P.; Meir, R. A.; Marshall-Gradisnik, S. M. (2007). "The Effect of Five Weeks of Tribulus terrestris Supplementation on Muscle Strength and Body Composition During Preseason Training in Elite Rugby League Players". The Journal of Strength & Conditioning Research. 21 (2): 348–53. doi:10.1519/R-18395.1. PMID 17530942.
- Asadmobini, Atefeh; Bakhtiari, Mitra; Khaleghi, Sara; Esmaeili, Farzaneh; Mostafaei, Ali (April 2017). "The effect of Tribulus terrestris extract on motility and viability of human sperms after cryopreservation". Cryobiology. 75: 154–159. doi:10.1016/j.cryobiol.2017.02.005. ISSN 1090-2392. PMID 28216339.
- Gauthaman K, Adaikan PG, Prasad RN (2002). "Aphrodisiac properties of Tribulus Terrestris extract (Protodioscin) in normal and castrated rats". Life Sciences. 71 (12): 1385–96. doi:10.1016/S0024-3205(02)01858-1. PMID 12127159.
- Bucci LR (2000). "Selected herbals and human exercise performance". The American Journal of Clinical Nutrition. 72 (2 Suppl): 624S–36S. doi:10.1093/ajcn/72.2.624S. PMID 10919969.
- Gauthaman K, Ganesan AP (Jan 2008). "The hormonal effects of Tribulus terrestris and its role in the management of male erectile dysfunction—an evaluation using primates, rabbit and rat". Phytomedicine. 15 (1–2): 44–54. doi:10.1016/j.phymed.2007.11.011. PMID 18068966.
- Neychev VK, Mitev VI (Oct 2005). "The aphrodisiac herb Tribulus terrestris does not influence the androgen production in young men". Journal of Ethnopharmacology. 101 (1–3): 319–23. doi:10.1016/j.jep.2005.05.017. PMID 15994038.
- Brown GA, Vukovich MD, Reifenrath TA, et al. (Sep 2000). "Effects of anabolic precursors on serum testosterone concentrations and adaptations to resistance training in young men". International Journal of Sport Nutrition and Exercise Metabolism. 10 (3): 340–59. PMID 10997957.
- Samani, N. B.; Jokar, A; Soveid, M; Heydari, M; Mosavat, S. H. (2016). "Efficacy of the Hydroalcoholic Extract of Tribulus terrestris on the Serum Glucose and Lipid Profile of Women With Diabetes Mellitus: A Double-Blind Randomized Placebo-Controlled Clinical Trial". J Evid Based Complementary Altern Med. 21 (4): NP91–7. doi:10.1177/2156587216650775. PMID 27255456.
- Akhtari E, et al. (Apr 2014). "Tribulus terrestris for treatment of sexual dysfunction in women: randomized double-blind placebo - controlled study". Daru. 22: 40. doi:10.1186/2008-2231-22-40. PMC 4045980. PMID 24773615.
- Templeton, Amelia (2014-06-16). "Irrigon Oregon Offers Dollar Bounty For Prickly Invasive Weed". OPB News. Retrieved 2014-06-17.
- Talasaz, A. H.; Abbasi, M.-R.; Abkhiz, S.; Dashti-Khavidaki, S. (2010). "Tribulus terrestris-induced severe nephrotoxicity in a young healthy male". Nephrology Dialysis Transplantation. 25 (11): 3792–3793. doi:10.1093/ndt/gfq457. PMID 20667992.
- Dinchev, Dragomir (May 2007). "Distribution of steroidal saponins in Tribulus terrestris from different geographical regions". Phytochemistry. 69 (1): 176–186. doi:10.1016/j.phytochem.2007.07.003. PMID 17719068 – via Elsevier.
- Gauthaman K, Ganesan AP, Prasad RN (2003). "Sexual effects of puncturevine (Tribulus terrestris) extract (protodioscin): an evaluation using a rat model". Journal of Alternative and Complementary Medicine. 9 (2): 257–65. doi:10.1089/10755530360623374. PMID 12804079.
- Hong CH, Hur SK, Oh OJ, Kim SS, Nam KA, Lee SK (2002). "Evaluation of natural products on inhibition of inducible cyclooxygenase (COX-2) and nitric oxide synthase (iNOS) in cultured mouse macrophage cells". J. Ethnopharmacol. 83 (1–2): 153–159. doi:10.1016/S0378-8741(02)00205-2. PMID 12413723.
- Bourke CA, Stevens GR, Carrigan MJ (Jul 1992). "Locomotor effects in sheep of alkaloids identified in Australian Tribulus terrestris". Australian Veterinary Journal. 69 (7): 163–165. doi:10.1111/j.1751-0813.1992.tb07502.x. PMID 1445080.