Talk:Polyketide

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 27 September 2021 and 3 December 2021. Further details are available on the course page. Student editor(s): Abnerndabad. Peer reviewers: Chunshengyan, Pin Chun Chen.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 06:55, 17 January 2022 (UTC)

Untitled

From my research in the topic, I think that modification domains (i.e. DH, KR, etc.) modify the group added in the previous module, not the newest addition. I could be wrong on this, but i'm pretty sure that's how it is. If it's wrong someone change my edit back. Zoffoperskof 10:52, 13 December 2006 (UTC)

Template help

If anyone has time, the {{Polyketides}} template would really benefit from your expertise. Thanks! :) Willow 19:08, 27 January 2007 (UTC)

Assessment comment

The comment(s) below were originally left at Talk:Polyketide/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

This seems to be a more obscure topic than others in the "high" category, so I've adjusted the rating to "mid". - tameeria 20:57, 18 February 2007 (UTC)

Last edited at 17:36, 15 February 2009 (UTC). Substituted at 03:11, 30 April 2016 (UTC)

Definition of ketide and polyketide

I think this article would be improved if the terms "ketide" and "polyketide" were better defined. Therefore, I am going to include those definitions as part of the article. The sources for the definitions are: https://en.oxforddictionaries.com/definition/polyketide https://en.oxforddictionaries.com/definition/ketide

This is what I will add:

"A ketide is a an organic compound having a carbonyl group (-CO-) adjacent to a methylene group (-CH2-). A polyketide is a compound which includes multiple ketide monomers (-CO-CH2-CO-CH2-). Some polyketides don't actually have multiple ketide monomers, but they are often synthesized from ketide monomers."

I am also going to add a comment to the effect that the term "polyketide" is poorly defined because I have consulted the following contemporary textbooks in organic chemistry and biochemistry and I have not found a definition in any of them.

Organic chemistry, 2013, by Solomons

Schaum's organic chemistry, 4th ed, by Meislich

Organic chemistry, 2012, by Clayden

Organic chemistry, 1992, by Morrison and Boyd

Lehninger principles of biochemistry, 2013, by Nelson — Preceding unsigned comment added by 70.36.134.209 (talk) 22:23, 19 September 2018 (UTC)

I am guessing that most editors would prefer a chemistry source vs OED for definitions. Check this out for "polyketide":

"Natural compounds containing alternating carbonyl and methylene groups ('β-polyketones'), biogenetically derived from repeated condensation of acetyl coenzyme A (via malonyl coenzyme A), and usually the compounds derived from them by further condensations. Considered by many to be synonymous with the less frequently used terms acetogenins and ketides."

https://goldbook.iupac.org/html/P/P04734.html.--Smokefoot (talk) 23:26, 19 September 2018 (UTC)