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editParietal cells don't secrete Gastrin - G Cells do (Endocrine cells of the stomach). They DO secrete GIF - Gastric Intrinsic Factor - which binds Vitamin B12. Deficiency of GIF leads to Pernicious Anemia due to the inability to bind B12.
The article says gastrin binds to parietal cells using CCK2 receptors. However, the diagram shows CCKB receptors. I am not a expert on the material (is it CCK2 or CCKB?)but there should be unity among these things.
- CCKB and CCK2 are the same thing. Refer to CCK_receptor. Xquizit Decorum (talk) 04:35, 27 December 2011 (UTC)
Confusing
editTHIS ARTICLE IS EXTREMELY CONFUSING to anyone without a degree in Biology. For instance, I have no idea what this means: "Parietal cells produce gastric acid (hydrochloric acid) in response to histamine (via H2 receptors), acetylcholine (M3 receptors) and gastrin (CCK2 receptors). The histamine receptors act by increasing intracellular cAMP, whereas the muscarinic and gastrin receptors increase intracellular Ca2+ levels. Both cAMP and Ca2+ acts via protein kinases to increase the transport of acid into the stomach." Please help.
- Please sign your posts with four tildes (~~~~) and use the "new section" tab to add a post to talk pages, it makes things a little easier for us. :) I've gone through and added several wikilinks in the paragraph you mention, to make it easier to find the related information. Unfortunately, cell biology is a very complex topic, so extensive reading is always required - there's just no way to make it simple! Hopefully, the added links will help you to better understand the topic, if not, please come back and leave further notes so we can continue to address the article. Regards. Franamax (talk) 00:20, 9 March 2009 (UTC)
Prostaglandins
editShouldn't these be added to the regulation section? — Preceding unsigned comment added by Vokesk (talk • contribs) 02:48, 10 February 2014 (UTC)