Testis-specific Y-encoded-like protein 2 is a protein that in humans is encoded by the TSPYL2 gene.[5][6][7]
| TSPYL2 |
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| Identifiers |
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| Aliases | TSPYL2, CDA1, CINAP, CTCL, DENTT, HRIHFB2216, NP79, SE204, TSPX, TSPY-like 2, TSPY like 2 |
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| External IDs | OMIM: 300564 MGI: 106244 HomoloGene: 11140 GeneCards: TSPYL2 |
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| RNA expression pattern |
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| Bgee | | Human | Mouse (ortholog) |
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| Top expressed in | - anterior pituitary
- gastric mucosa
- tibial nerve
- left uterine tube
- canal of the cervix
- nucleus accumbens
- sural nerve
- cingulate gyrus
- Brodmann area 9
- ascending aorta
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| | Top expressed in | - dorsomedial hypothalamic nucleus
- superior frontal gyrus
- paraventricular nucleus of hypothalamus
- ventromedial nucleus
- arcuate nucleus
- cerebellar cortex
- median eminence
- lateral hypothalamus
- suprachiasmatic nucleus
- ventral tegmental area
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| | More reference expression data |
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| BioGPS | |
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| Wikidata |
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References
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- ^ a b c GRCh38: Ensembl release 89: ENSG00000184205 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000041096 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Ozbun LL, You L, Kiang S, Angdisen J, Martinez A, Jakowlew SB (Apr 2001). "Identification of differentially expressed nucleolar TGF-beta1 target (DENTT) in human lung cancer cells that is a new member of the TSPY/SET/NAP-1 superfamily". Genomics. 73 (2): 179–93. doi:10.1006/geno.2001.6505. PMID 11318608.
- ^ Chai Z, Sarcevic B, Mawson A, Toh BH (Sep 2001). "SET-related cell division autoantigen-1 (CDA1) arrests cell growth". J Biol Chem. 276 (36): 33665–74. doi:10.1074/jbc.M007681200. PMID 11395479.
- ^ "Entrez Gene: TSPYL2 TSPY-like 2".
Further reading
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- Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
- Eichmuller S, Usener D, Dummer R, et al. (2001). "Serological detection of cutaneous T-cell lymphoma-associated antigens". Proc. Natl. Acad. Sci. U.S.A. 98 (2): 629–34. doi:10.1073/pnas.021386498. PMC 14639. PMID 11149944.
- Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs". Genome Res. 11 (3): 422–35. doi:10.1101/gr.GR1547R. PMC 311072. PMID 11230166.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Wang GS, Hong CJ, Yen TY, et al. (2004). "Transcriptional modification by a CASK-interacting nucleosome assembly protein". Neuron. 42 (1): 113–28. doi:10.1016/S0896-6273(04)00139-4. PMID 15066269.
- Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
- Santama N, Ogg SC, Malekkou A, et al. (2006). "Characterization of hCINAP, a novel coilin-interacting protein encoded by a transcript from the transcription factor TAFIID32 locus". J. Biol. Chem. 280 (43): 36429–41. doi:10.1074/jbc.M501982200. PMID 16079131.
- Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
- Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
- Radke JR, Donald RG, Eibs A, et al. (2006). "Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development". PLOS Pathog. 2 (10): e105. doi:10.1371/journal.ppat.0020105. PMC 1626100. PMID 17069459.
- Tu Y, Wu W, Wu T, et al. (2007). "Antiproliferative autoantigen CDA1 transcriptionally up-regulates p21(Waf1/Cip1) by activating p53 and MEK/ERK1/2 MAPK pathways". J. Biol. Chem. 282 (16): 11722–31. doi:10.1074/jbc.M609623200. PMID 17317670.
