TIMM23

Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the TIMM23 gene.

TIMM23B
Identifiers
Aliases	TIMM23B, TIMM23, bA592B15.7, translocase of inner mitochondrial membrane 23 homolog B
External IDs	HomoloGene: 140621 GeneCards: TIMM23B
Gene location (Human) Chr. Chromosome 10 (human) Band 10q11.23 Start 49,942,049 bp End 49,974,850 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in tibialis anterior muscle deltoid muscle quadriceps femoris muscle vastus lateralis muscle biceps brachii pancreatic ductal cell nipple jejunal mucosa caput epididymis gastrocnemius muscle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function protein-transporting ATPase activity molecular function protein transmembrane transporter activity Cellular component membrane integral component of mitochondrial inner membrane TIM23 mitochondrial import inner membrane translocase complex integral component of membrane mitochondrion mitochondrial inner membrane cellular component Biological process protein import into mitochondrial matrix intracellular protein transport protein transport biological process Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 100652748 n/a Ensembl ENSG00000204152 n/a UniProt Q5SRD1 n/a RefSeq (mRNA) NM_001290117 NM_001290118 NM_001365871 n/a RefSeq (protein) NP_001277046 NP_001277047 NP_001352800 n/a Location (UCSC) Chr 10: 49.94 – 49.97 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

See also

• Mitochondria Inner Membrane Translocase
• TIMM17A
• TIMM22
• TIMM44

Further reading

• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Guo Y, Cheong N, Zhang Z, et al. (2004). "Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death". J. Biol. Chem. 279 (23): 24813–25. doi:10.1074/jbc.M402049200. PMID 15044455.
• Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
• Yamamoto H, Esaki M, Kanamori T, et al. (2002). "Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes". Cell. 111 (4): 519–28. doi:10.1016/S0092-8674(02)01053-X. PMID 12437925. S2CID 18869447.
• Moro F, Sirrenberg C, Schneider HC, et al. (1999). "The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix". EMBO J. 18 (13): 3667–75. doi:10.1093/emboj/18.13.3667. PMC 1171444. PMID 10393182.
• Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
• Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.