Sergio Bueno started off his professional football career with Deportivo Neza in the 1983-84 tournament against Puebla FC where he came in as substitute in the 88 minute. He played with Coyotez Neza from 1983-88 where he played 99 league matches and scored 3 goals. In 1988, he transferred to Atlante F.C. where he only played for one year before transferring again this time to Querétaro F.C. where he was a key player. In 1991, he was sent on loan to Morelia where he played in 27 of the 38 matches before returning to Querétaro F.C. where he stayed till 1994. In 1995, he transferred to Veracruz where he spend most of the tournament as a substitute. In 1996, he signed with Celaya where he spent most of the tournament on the bench mentoring the young players. His last club was Puebla FC where he only played in 15 matches before announcing his retirement at the end of the tournament.