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Phosphoribosyl pyrophosphate (PRPP) is a pentosephosphate.
3D model (JSmol)
|Molar mass||390.07 g/mol|
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
|what is ?)(|
It plays a role in transferring phospho-ribose groups in several reactions:
Increased levels of PRPP are present in Lesch–Nyhan Syndrome. Decreased levels of hypoxanthine guanine phosphoribosyl transferase (HGPRT) causes this accumulation, as PRPP is a substrate used by HGPRT during purine salvage.