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He was bishop of Le Mans in 1476. He was bishop of Thérouanne 1496 to 1513, and bishop of Saint-Pons in 1509, when his nephew died, and until 1512, when he resigned in favour of François-Guillaume de Castelnau de Clermont-Lodève. He was abbot at the abbey of Jumièges in 1510.
His father was Cardinal Thibaud de Luxembourg.
- From 1495. He was bishop of Albano in 1509, bishop of Frascati 1511.
- , French.
- "«HISTOIRE DE L'ABBAYE ROYALE DE SAINT-PIERRE DE JUMIÈGES», ÉDITION DE JULIEN LOTH; 15". Archived from the original on 2009-05-25. Retrieved 2007-06-20.