Nick Knight or Nicholas Night may refer to:
- Nick Knight (cricketer) (born 1969), a former England international cricketer
- Nick Knight (photographer) (born 1958), British fashion photographer, documentary photographer, and web publisher
- Nick Knight (professor), Professor of Asian Studies
- Nick Knight (born 1959), stage name of American pornographic actor Mickey G.
- Nicholas Egbert Knight (1866 – 1946), a South Dakota politician