The Moscow–Constantinople schism refers to either of two schisms within the Eastern Orthodox Church wherein the Russian Orthodox Church severed full communion with the Ecumenical Patriarchate of Constantinople:
- Third Rome, the Russian assertion of de facto primacy in the Orthodox communion following the 1453 fall of Constantinople
- Raskol, the 17th-century schism within the Russian Orthodox Church with anti-Reform members which eventually led to the formation of the Old Believers sects
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