In enzymology, a methylene-fatty-acyl-phospholipid synthase (EC 2.1.1.16) is an enzyme that catalyzes the chemical reaction
| methylene-fatty-acyl-phospholipid synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 2.1.1.16 | ||||||||
| CAS no. | 37256-90-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- S-adenosyl-L-methionine + phospholipid olefinic fatty acid S-adenosyl-L-homocysteine + phospholipid methylene fatty acid
Thus, the two substrates of this enzyme are S-adenosyl methionine and phospholipid olefinic fatty acid, whereas its two products are S-adenosylhomocysteine and phospholipid methylene fatty acid.
This enzyme belongs to the family of transferases, specifically those transferring one-carbon group methyltransferases. The systematic name of this enzyme class is S-adenosyl-L-methionine:unsaturated-phospholipid methyltransferase (methenylating). This enzyme is also called unsaturated-phospholipid methyltransferase.
References edit
- Akamatsu Y, Law JH (1970). "Enzymatic alkylenation of phospholipid fatty acid chains by extracts of Mycobacterium phlei". J. Biol. Chem. 245 (4): 701–8. PMID 4313604.
