Methyl caffeate

Methyl caffeate is an ester of a hydroxycinnamic acid, a naturally occurring phenolic compound. It is an α-Glucosidase inhibitor.[1]

Methyl caffeate
Methyl caffeate.PNG
Chemical structure of methyl caffeate
IUPAC name
methyl (E)-3-(3,4-dihydroxyphenyl)prop-2-enoate
Other names
Caffeic acid methyl ester
Methyl 3,4-dihydroxycinnamate
3D model (JSmol)
ECHA InfoCard 100.236.052 Edit this at Wikidata
Molar mass 194.18 g/mol
Related compounds
Related compounds
Caffeic acid, Ethyl caffeate
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Natural occurrencesEdit

Methyl caffeate can be found in the fruit of Solanum torvum.[2]

Health effectEdit

Methyl caffeate shows an antidiabetic effect in streptozotocin-induced diabetic rats.[2]


  1. ^ Takahashi, Keisuke; Yoshioka, Yasuyuki; Kato, Eisuke; Katsuki, Shigeki; Iida, Osamu; Hosokawa, Keizo; Kawabata, Jun (2014). "Methyl Caffeate as an α-Glucosidase Inhibitor from Solanum torvum Fruits and the Activity of Related Compounds". Bioscience, Biotechnology, and Biochemistry. 74 (4): 741–745. doi:10.1271/bbb.90789. PMID 20378981. S2CID 23067847.
  2. ^ a b Antihyperglycemic activity and antidiabetic effect of methylcaffeate isolated from Solanum torvum Swartz. fruit in streptozotocin induced diabetic rats. Gopalsamy Rajiv Gandhi, Savarimuthu Ignacimuthu, Michael Gabriel Paulraj, Ponnusamy Sasikumar, European Journal of Pharmacology, Volume 670, Issues 2–3, 30 November 2011, Pages 623–631, doi:10.1016/j.ejphar.2011.09.159