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Masohi is a coastal town on the Indonesian island of Seram. It is the capital of the Central Maluku Regency (Kebupaten Maluku Tengah). It was the site of a detention camp for political prisoners in the 1970s. The headquarters of Manusela National Park is located in Masohi.
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The Maluku sectarian conflict impacted Masohi at the end of 1999 and in early 2000. A fresh outbreak of violence occurred in 2008 in Masohi over alleged blasphemy by a teacher. Dozens of houses were burnt, as well as a church and a village hall. Five injuries were reported.
Points of interest include the cave Goa Akohi (near Tamilouw village) and a small lake, Ihu Allah.