Manuel Bryennios or Bryennius (Greek: Μανουήλ Βρυέννιος; c. 1275 – c. 1340) was a Byzantine scholar who flourished in Constantinople about 1300 teaching astronomy, mathematics and musical theory. His only surviving work is the Harmonika (Greek: Ἁρμονικά), which is a three-volume codification of Byzantine musical scholarship based on the classical Greek works of Ptolemy, Nicomachus, and the Neopythagorean authors on the numerological theory of music. One of Bryennios's students was Theodore Metochites, the grand logothete during the reign of Emperor Andronikos II Palaiologos (r. 1272–1328). Metochites studied astronomy under Bryennios.
- Freely, John (2012). Flame of Miletus: The Birth of Science in Ancient Greece (and How it Changed the World). London and New York: I.B. Tauris. ISBN 978-1-78-076051-3.
- NDSU Department of Mathematics (1997). "Mathematics Genealogy Project". Mathematics Genealogy Project. American Mathematical Society. Retrieved 19 July 2015.
- Nicolaidis, Efthymios (2011). Science and Eastern Orthodoxy: From the Greek Fathers to the Age of Globalization. Baltimore, MD: The Johns Hopkins University Press. ISBN 978-1-42-140298-7.