The daughter of Isaac Steibel, she married, in 1889, Gilbert Ellis Samuel, son of Edwin Samuel and brother of Sir Stuart Samuel and Herbert Samuel, Viscount Samuel. From its foundation in 1908 until its dissolution in 1918, she served as honorary secretary of the Conservative Women's Franchise Association, a non-militant women's suffrage movement. In 1919, she was elected to Chelsea Borough Council for the Municipal Reform Party. In August 1914, she co-founded the War Refugees' Committee. She was a member of the Managing Committee and head of the Health Section throughout the First World War.
In 1918, she was appointed Officer of the Order of the British Empire (OBE) for her refugee work. She was appointed Dame Commander of the Order of the British Empire (DBE) in the 1920 civilian war honours.