Leishmania tropica

Leishmania tropica is a species of flagellate parasites that infects humans and hyraxes, and the cause of the disease Leishmaniasis Recidivans, a form of cutaneous leishmaniasis.[1] L. tropica infection results in non-ulcerating disease.

Leishmania tropica
Leishmania tropica promastigotes.jpg
Promastigotes of Leishmania tropica. Giemsa stain, 10×100.
Scientific classification edit
Domain: Eukaryota
Phylum: Euglenozoa
Class: Kinetoplastea
Order: Trypanosomatida
Genus: Leishmania
Species:
L. tropica
Binomial name
Leishmania tropica
Wright, 1903

Fusion and hybridization of different L. tropica strains can be efficiently induced in vitro by exposure of promastigotes (a stage of the life cycle) to DNA damage stress.[2] The fused cells do not undergo meiosis and are mostly tetraploid.[citation needed]

Cutaneous leishmaniasis in North Africa; Leishmania tropica infected areas are in red[3]

ReferencesEdit

  1. ^ Gitari JW, Nzou SM, Wamunyokoli F, Kinyeru E, Fujii Y, Kaneko S, Mwau M (2018). "Leishmaniasis recidivans by Leishmania tropica in Central Rift Valley Region in Kenya". Int J Infect Dis. 74: 109–116. doi:10.1016/j.ijid.2018.07.008. PMID 30017946.
  2. ^ Louradour I, Ferreira TR, Duge E, Karunaweera N, Paun A, Sacks D. Stress conditions promote Leishmania hybridization in vitro marked by expression of the ancestral gamete fusogen HAP2 as revealed by single-cell RNA-seq. Elife. 2022;11:e73488. Published 2022 Jan 7. doi:10.7554/eLife.73488
  3. ^ Aoun, K.; Bouratbine, A. (2014). "Cutaneous Leishmaniasis in North Africa: a review". Parasite. 21: 14. doi:10.1051/parasite/2014014. PMC 3952656. PMID 24626301.

Further readingEdit

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