KCNJ13

Potassium inwardly-rectifying channel, subfamily J, member 13 (KCNJ13) is a human gene encoding the K_ir7.1 protein.

KCNJ13
Identifiers
Aliases	KCNJ13, KIR1.4, KIR7.1, LCA16, SVD, potassium voltage-gated channel subfamily J member 13, potassium inwardly rectifying channel subfamily J member 13
External IDs	OMIM: 603208 MGI: 3781032 HomoloGene: 55638 GeneCards: KCNJ13
Gene location (Human) Chr. Chromosome 2 (human) Band 2q37.1 Start 232,765,802 bp End 232,776,565 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 D|1 Start 87,314,085 bp End 87,322,451 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in retinal pigment epithelium jejunal mucosa sural nerve Achilles tendon duodenum bone marrow cells corpus callosum sperm seminal vesicula kidney Top expressed in retinal pigment epithelium iris otolith organ utricle ciliary body sciatic nerve olfactory epithelium stria vascularis right lung lobe left lung lobe More reference expression data BioGPS More reference expression data
Gene ontology Molecular function inward rectifier potassium channel activity voltage-gated ion channel activity Cellular component integral component of membrane integral component of plasma membrane membrane Biological process potassium ion transport regulation of ion transmembrane transport ion transport potassium ion import across plasma membrane Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 3769 100040591 Ensembl ENSG00000115474 ENSMUSG00000079436 UniProt O60928 P86046 RefSeq (mRNA) NM_002242 NM_001172416 NM_001172417 NM_001110227 RefSeq (protein) NP_001165887 NP_001165888 NP_002233 NP_001103697 Location (UCSC) Chr 2: 232.77 – 232.78 Mb Chr 1: 87.31 – 87.32 Mb PubMed search
Wikidata
View/Edit Human View/Edit Mouse

See also

• Inward-rectifier potassium ion channel

Further reading

• Kubo Y, Adelman JP, Clapham DE, Jan LY, Karschin A, Kurachi Y, Lazdunski M, Nichols CG, Seino S, Vandenberg CA (December 2005). "International Union of Pharmacology. LIV. Nomenclature and molecular relationships of inwardly rectifying potassium channels". Pharmacological Reviews. 57 (4): 509–26. doi:10.1124/pr.57.4.11. PMID 16382105. S2CID 11588492.
• Krapivinsky G, Medina I, Eng L, Krapivinsky L, Yang Y, Clapham DE (May 1998). "A novel inward rectifier K+ channel with unique pore properties". Neuron. 20 (5): 995–1005. doi:10.1016/S0896-6273(00)80480-8. PMID 9620703. S2CID 16356235.
• Partiseti M, Collura V, Agnel M, Culouscou JM, Graham D (August 1998). "Cloning and characterization of a novel human inwardly rectifying potassium channel predominantly expressed in small intestine". FEBS Letters. 434 (1–2): 171–6. doi:10.1016/S0014-5793(98)00972-7. PMID 9738472. S2CID 27138272.
• Döring F, Derst C, Wischmeyer E, Karschin C, Schneggenburger R, Daut J, Karschin A (November 1998). "The epithelial inward rectifier channel Kir7.1 displays unusual K+ permeation properties". The Journal of Neuroscience. 18 (21): 8625–36. doi:10.1523/JNEUROSCI.18-21-08625.1998. PMC 6793533. PMID 9786970.
• Derst C, Döring F, Preisig-Müller R, Daut J, Karschin A, Jeck N, Weber S, Engel H, Grzeschik KH (December 1998). "Partial gene structure and assignment to chromosome 2q37 of the human inwardly rectifying K+ channel (Kir7.1) gene (KCNJ13)". Genomics. 54 (3): 560–3. doi:10.1006/geno.1998.5598. PMID 9878260.
• Nakamura N, Suzuki Y, Sakuta H, Ookata K, Kawahara K, Hirose S (September 1999). "Inwardly rectifying K+ channel Kir7.1 is highly expressed in thyroid follicular cells, intestinal epithelial cells and choroid plexus epithelial cells: implication for a functional coupling with Na+,K+-ATPase". The Biochemical Journal. 342 ( Pt 2) (2): 329–36. doi:10.1042/0264-6021:3420329. PMC 1220469. PMID 10455019.
• Kimura K, Wakamatsu A, Suzuki Y, Ota T, Nishikawa T, Yamashita R, Yamamoto J, Sekine M, Tsuritani K, Wakaguri H, Ishii S, Sugiyama T, Saito K, Isono Y, Irie R, Kushida N, Yoneyama T, Otsuka R, Kanda K, Yokoi T, Kondo H, Wagatsuma M, Murakawa K, Ishida S, Ishibashi T, Takahashi-Fujii A, Tanase T, Nagai K, Kikuchi H, Nakai K, Isogai T, Sugano S (January 2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes". Genome Research. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.

External links

• KCNJ13+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.