Juana and one of her daughters, painted by Jaime Serra in the mid-fourteenth century
|Queen consort of Castile and León|
|Died||27 March 1381 (aged 41–42)|
|Spouse||Henry II of Castile|
|Issue||John I of Castile|
Eleanor, Queen of Navarre
|House||Castilian House of Ivrea|
|Father||Juan Manuel, Prince of Villena|
|Mother||Blanca Núñez de Lara|
She was the daughter of Juan Manuel, Prince of Villena (1282–1348) and his second wife Blanca Núñez de Lara de La Cerda. Her mother Blanca (d. 1347) was a descendant of the lords of Biscay and of Lara and of Alfonso X's eldest son, Fernando de la Cerda. She was the last legitimate member of the House of Ivrea.
Her father had been for five years a serious enemy of King Alfonso XI, his former protégé, and the king wished to neutralize or absorb the might of the Peñafiel family. Although Juana was not the heiress (yet), already in her youth she had to go along with royal wishes. The king's very influential concubine, Leonor de Guzmán, wanted to obtain some high prestige and property to her eldest son and had her eyes on the young Juana. On 27 July 1350 her brother and guardian, Fernando Manuel of Peñafiel, had to marry his young sister to Henry (1333–79), eldest of the illegitimate sons of Alfonso XI of Castile. This brought Henry certain lands.
However it was later that Juana's relatives' heirless deaths made Juana the great heiress she turned out to be, while her husband became threat to the royal power. In 1369, he became King Henry II of Castile, after he deposed and murdered his half-brother to take the throne.
They had the following children:
In 1361 (at the death of her teenage niece Blanca, daughter of her brother Fernando Manuel who himself had died in c 1350 without other children) she inherited Villena, Escalona and Peñafiel. Because Juana was a maternal granddaughter of La Palomilla, from her another cousin, Isabel de Lara who was murdered in 1361  and her young daughter Florentina  (d after 1365), she also inherited Lara and Biscay. In 1369, she became queen of Castile and León.
When in 1381 she died and left her inheritance to her son, Biscay finally was united with Castile, and ultimately Spain. The Basque people remember her for that.
|Family tree of Juana Manuel|
- Marek, Miroslav. "(Blanca's death)". Genealogy.EU.[self-published source][better source needed]
- Cawley, Charles, (inheritance of the 'greatest' castilian patrimony), Medieval Lands database, Foundation for Medieval Genealogy,[self-published source][better source needed]
- Marek, Miroslav. "(Isabel's death)". Genealogy.EU.[self-published source][better source needed]
- Marek, Miroslav. "(Florentina's death)". Genealogy.EU.[self-published source][better source needed]
Juana ManuelBorn: circa 1339 Died: 27 March 1381
Blanche of Bourbon
| Queen consort of Castile and León
Eleanor of Aragon
| Lady of Villena,
Escalona and Peñafiel
|Incorporated into the|
Crown of Castile
| Lord of Biscay and Lara
John II of Castile