James O'Shaughnessy may refer to:
- James O'Shaughnessy (investor), American investor, the founder of O'Shaughnessy Asset Management, and the founder of O'Shaughnessy Ventures
- James O'Shaughnessy (American football), American football tight end
- James O'Shaughnessy, Baron O'Shaughnessy, British politician
This disambiguation page lists articles about people with the same name.
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