Ivar Karl Ugi

Ivar Karl Ugi (9 September 1930 in Saaremaa, Estonia – 29 September 2005 in Munich) was an Estonian-born German chemist who made major contributions to organic chemistry. He is known for the research on multicomponent reactions, yielding the Ugi reaction.

Ivar Ugi
Born(1930-09-09)9 September 1930
Died29 September 2005(2005-09-29) (aged 75)
NationalityEstonian, German
Alma materUniversity of Tübingen
Ludwig Maximilian University of Munich
Known forUgi reaction
Scientific career
InstitutionsLudwig Maximilian University of Munich
University of Southern California
Technical University of Munich
Doctoral advisorRolf Huisgen


After he went to Germany from Estonia in 1941 he began his studies of chemistry in 1949 at the University of Tübingen until 1951. He became Dr. rer. nat. in 1954 at the Ludwig Maximilian University of Munich. He did his habilitation 1960 at the same university. After a short but very successful career in industry at Bayer from 1962 until 1968 when he joined the University of Southern California at Los Angeles.

From 1971 he worked at the Technical University of Munich, and was an emeritus from 1999 until his death in 2005.

Research and developmentEdit

The one pot reaction of a ketone or aldehyde, an amine, an isocyanide and a carboxylic acid to form a bis-amide is generally known as Ugi reaction.

Major worksEdit

  • Ugi, I. (1962). "The α-Addition of Immonium Ions and Anions to Isonitriles Accompanied by Secondary Reactions". Angew. Chem. Int. Ed. Engl. 1 (1): 8–21. doi:10.1002/anie.196200081.


  • Curriculum Vitae at TUM
  • Peter Lemmen; Eric Fontain; Johannes Bauer (2006). "Ivar K. Ugi (1930-2005): Multicomponent Reactions, Computer and Phosphorus Chemistry". Angewandte Chemie International Edition. 45 (2): 193–193. doi:10.1002/anie.200503978.