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Hegesistratus (Ancient Greek: Ἡγησίστρατος) is an ancient Greek name. Some people with this name were:
- A Greek diviner for Mardonius during the Greco-Persian Wars. Originally an Elean, he had been captured by the Spartans and put in bonds. He escaped by cutting off a piece of his own foot and replaced it with a wooden one; however, he was captured again at Zacynthus and put to death. This story is mentioned in the ninth book (chapter 37) of the Histories written by Herodotus.
- An emissary from Samos to the Greeks before the Battle of Mycale.
- A despot of Sigeum.
- An Ephesian committed a murder in his family, and fled to Delphi; on consulting the oracle what place to settle in, the answer was, that when he should come to a place where he should see the country people dancing with garlands of olive-leaves, he should settle there. He travelled and found what the oracle told him, and there built the city Elaeus.
- Democritus was the son of Hegesistratus, though some say of Athenocritus, and others of Damasippus.
- The governor of Miletus, during the Siege of Miletus by Alexander the Great.