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In human mitochondrial genetics, the Haplogroup CZ is a human mitochondrial DNA (mtDNA) haplogroup.

Haplogroup CZ
DescendantsC, Z
Defining mutations249d[1]



Haplogroup CZ is a descendant of haplogroup M and is a parent to the haplogroups C and Z. The C and Z subclades share a common ancestor dated to approximately 45,000 years ago.[2]


Today, CZ is found in eastern Asian, Central Asian, Siberian, indigenous American, and European populations, and is most common in Siberian populations. It is recognized by a genetic marker at 249d.



This phylogenetic tree of haplogroup CZ subclades is based on the paper by Mannis van Oven and Manfred Kayser Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation[1] and subsequent published research.

  • M
    • M8
      • CZ
        • C
        • Z

See alsoEdit


  1. ^ a b van Oven, Mannis; Manfred Kayser (13 Oct 2008). "Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation". Human Mutation. 30 (2): E386–E394. doi:10.1002/humu.20921. PMID 18853457. Archived from the original on 4 December 2012. Retrieved 2009-05-20.
  2. ^ Sebastian Lippold; et al. (2014). "Human paternal and maternal demographic histories: insights from high-resolution Y chromosome and mtDNA sequences". bioRxiv 001792.

External linksEdit