Haplogroup A-P305 also known as A1 is a human Y-chromosome DNA haplogroup. Like its parent haplogroup haplogroup A0-T (A-L1085), A1 includes the vast majority of living human males. It emerged in Africa approximately 161,300 years ago. [1] By comparison, members of its sole sibling subclade, haplogroup A0 – the only other primary subclade of haplogroup A0-T – are found mostly in Africa.
| Haplogroup A1 | |
|---|---|
| Possible time of origin | 161,300 years BP[1] |
| Possible place of origin | Africa |
| Ancestor | A0-T |
| Descendants | A1a and A1b |
| Defining mutations | P305 |
Basal, undivergent A-P305* is largely restricted to populations native to Africa, though a handful of cases have been reported in Europe and Western Asia. A-P305* is found at its highest rates in Bakola Pygmies (South Cameroon) at 8.3% and Berbers from Tunisia at 1.5%[2] and in Ghana.[3] The clade also achieves high frequencies in the Bushmen hunter-gatherer populations of Southern Africa, followed closely by many Nilotic groups in Eastern Africa. However, haplogroup A's oldest sub-clades are exclusively found in Central-Northwest Africa, where it, and consequently Y-chromosomal Adam, is believed to have originated about 140,000 years ago.[2] The clade has also been observed at notable frequencies in certain populations in Ethiopia, as well as some Pygmy groups in Central Africa.
Footnotes edit
- ^ a b "A1 YTree". www.yfull.com.
- ^ a b Cruciani F, Trombetta B, Massaia A, Destro-Bisol G, Sellitto D, Scozzari R (Jun 2011). "A revised root for the human Y chromosomal phylogenetic tree: the origin of patrilineal diversity in Africa". American Journal of Human Genetics. 88 (6): 814–8. doi:10.1016/j.ajhg.2011.05.002. PMC 3113241. PMID 21601174.
- ^ Scozzari R, Massaia A, D'Atanasio E, et al. (2012). "Molecular dissection of the basal clades in the human Y chromosome phylogenetic tree". PLOS ONE. 7 (11): e49170. Bibcode:2012PLoSO...749170S. doi:10.1371/journal.pone.0049170. PMC 3492319. PMID 23145109.
 | This genetics article is a stub. You can help Wikipedia by expanding it. |