HNLMS De Ruyter (Dutch: Hr.Ms. or Zr.Ms. De Ruyter) may refer to one of seven ships of the Royal Netherlands Navy named after Admiral Michiel Adriaenszoon de Ruyter (1607–1676):
- HNLMS De Ruyter (1799), was a 68-gun frigate that the British Royal Navy captured in 1799 and took into service as a storeship. She was on her way to Falmouth, Jamaica, to serve as a prison hulk when a hurricane in September 1804 caused her to ground, wrecking her.
- HNLMS De Ruyter (1853), was a 54-gun frigate converted to steam power and then into a broadside ironclad in 1863
- HNLMS De Ruyter (1880), was an Atjeh-class unprotected cruiser
- HNLMS De Ruyter (1901), was a Koningin Regentes-class coastal defense ship
- HNLMS De Ruyter (1926), was an Admiralen-class destroyer. She was renamed Van Ghent to make way for the 1935 De Ruyter. She served in World War II and was wrecked on Bamidjo reef on 15 February 1942
- HNLMS De Ruyter (1935), was a unique light cruiser. She served in World War II and was sunk in the battle of the Java Sea on 28 February 1942.
- HNLMS De Ruyter (C801), launched in 1944, was a De Zeven Provinciën-class cruiser (laid down as De Zeven Provinciën, renamed after the sinking of the 1935 De Ruyter). She was sold to Peru in 1973 and renamed Almirante Grau
- HNLMS De Ruyter (1974), was a Tromp-class guided missile frigate
- HNLMS De Ruyter (F804), launched in 2002, is a De Zeven Provinciën-class frigate