Guillermo Ortiz may refer to:
- Guillermo Ortiz (Mexican footballer) (1939–2009), Mexican football forward
- Guillermo Ortiz Mondragón (1947-2021), Mexican Roman Catholic prelate
- Guillermo Ortiz Martínez (born 1948), former Governor of the Bank of Mexico
- Guillermo Ortiz Mayagoitia (born 1941), President of the Supreme Court
- Guillermo Ortiz (Argentine footballer) (born 1992), Argentine football centre-back
This disambiguation page lists articles about people with the same name.
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