Folie à deux
Folie à deux, shared psychosis, or shared delusional disorder is a psychiatric syndrome in which symptoms of a delusional belief and sometimes hallucinations are transmitted from one individual to another. The same syndrome shared by more than two people may be called folie à trois, folie à quatre, folie en famille ("family madness"), or even folie à plusieurs ("madness of several").
|Induced delusional disorder|
|Other names||Lasègue-Falret syndrome, induced delusional disorder, shared psychotic disorder|
Recent psychiatric classifications refer to the syndrome as shared psychotic disorder (DSM-IV – 297.3) and induced delusional disorder (F24) in the ICD-10, although the research literature largely uses the original name. This disorder is not in the current DSM (DSM-5). The disorder was first conceptualized in 19th-century French psychiatry by Charles Lasègue and Jean-Pierre Falret and is also known as Lasègue-Falret syndrome. The term is from French for "madness by two".
Signs and symptomsEdit
This syndrome is most commonly diagnosed when the two or more individuals concerned live in proximity and may be socially or physically isolated and have little interaction with other people. Various sub-classifications of folie à deux have been proposed to describe how the delusional belief comes to be held by more than one person:
- Folie imposée is where a dominant person (known as the 'primary', 'inducer' or 'principal') initially forms a delusional belief during a psychotic episode and imposes it on another person or persons (known as the 'secondary', 'acceptor' or 'associate') with the assumption that the secondary person might not have become deluded if left to his or her own devices. If the parties are admitted to hospital separately, then the delusions in the person with the induced beliefs usually resolve without the need of medication.
- Folie simultanée describes either the situation where two people considered to suffer independently from psychosis influence the content of each other's delusions so they become identical or strikingly similar, or one in which two people "morbidly predisposed" to delusional psychosis mutually trigger symptoms in each other.
Folie à deux and its more populous cousins are in many ways a psychiatric curiosity. The current Diagnostic and Statistical Manual of Mental Disorders states that a person cannot be diagnosed as being delusional if the belief in question is one "ordinarily accepted by other members of the person's culture or subculture" (see entry for delusion). It is not clear at what point a belief considered to be delusional escapes from the folie à... diagnostic category and becomes legitimate because of the number of people holding it. When a large number of people may come to believe obviously false and potentially distressing things based purely on hearsay, these beliefs are not considered to be clinical delusions by the psychiatric profession and are labelled instead as mass hysteria.
As with most psychological disorders, the extent and type of delusion varies, however it usually mimics the delusion of the inducer and is almost very similar to it. The inducer does not realize that they are making the other person sick but instead think they are helping by alerting the second person of what they deem to be "truth".
Type of delusionsEdit
Psychology Today magazine defines delusions as "fixed beliefs that do not change, even when a person is presented with conflicting evidence." There are 4 main types of delusions that are passed on from an inducer to a secondary person: bizarre delusions, non-bizarre delusions, mood-congruent delusions and mood-neutral delusions.
- Bizarre delusions are clearly implausible and not understood by peers within the same culture, even those with psychological disorders; for example, if one thought that all of their organs had been taken out and replaced by someone else's while they were asleep without leaving any scar and without their waking up. Not only is it impossible for someone to survive having all their organs taken out and replaced, but if they did survive they would be covered in scars, need bottles of anti-rejection and pain medication, would be in a crippling amount of pain, and would not be able to move.
- Non-bizarre delusions are common among those with personality disorders and are understood by people within the same culture. For example, if one thinks that the FBI is following them in unmarked cars and watching them via security cameras, they are having a non-bizarre delusion. While this is highly unlikely for the average person, it is possible and therefore understood by those around them.
- Mood-congruent delusions correspond to a person's emotions at the time, usually during an episode of mania or depression. For example, someone with this type of delusion may believe that they are going to win $2 million at the casino tonight, despite the fact that the majority of people who go to a casino walk away having lost money or in some cases leave with some money, but rarely over $100 and almost never $2 million. Similarly, someone in a depressive state may believe that their mother will get hit by lightning the next day, despite the fact that only about 240,000 people are injured by lightning strikes per year (out of a global population of approximately 7.57 billion as of 2019).
- Mood-neutral delusions are the opposite of mood-congruent delusions as they are unaffected by mood, and can be bizarre or non-bizarre; the formal definition provided by Mental Health Daily is "a false belief that isn't directly related to the person's emotional state." An example would be if one were steadily convinced that somebody had switched bodies with their neighbor, as the belief remains independent of whether they may be in a manic or depressive state.
As with most, if not all personality disorders, shared delusional disorder affects the psychological and social aspects of the person's life. Biologically, since most delusions are accompanied by fear and paranoia, they increase the amount of stress experienced. For example, if a woman believes that radiation from the sun is poisoning her food she is going to be extremely stressed and fearful for her life. Increased stress will negatively affect her physical health because stress increases blood pressure, heart rate and breathing rates which put her at risk of developing cardiovascular disease. Additionally, she will be at an increased risk of developing diabetes, becoming obese and the functioning of her immune system will be lessened as a result of stress. These health risks increase with the severity of the disease, especially if the condition is left untreated and becomes chronic, leading to the development of anxiety and depression.
In fact, delusional disorder puts those affected with it at a heightened risk of developing other psychological disorder such as anxiety and depression. This is because 55% of people with shared delusional disorder are genetically predisposed to psychological disorders like bipolar disorder, schizophrenia, anxiety, and depression...etc. This predisposition is usually triggered by the heightened state of fear, worry, and hopelessness experienced by those with shared delusional disorder (SDD) through increased levels of cortisol and therefore dopamine levels. Since shared delusional disorder itself is a very frightening and stressful disorder to live with, adding anxiety which is characterized by nervousness, worry, fear and apprehension  and depression, a state of despondency and dejection makes their life impossibly difficult.
The most obvious effect of shared personality disorder is probably the isolation from society. If a man believes that the FBI is stalking him or that there are people trying to hurt him, he is going to disassociate from society and stop talking to most people, especially if he senses any hostility or lack of belief in this delusion. Since shared delusional disorder usually occurs in those who are socially isolated, further isolation will only make the disorder worse as it will pull the secondary person closer to the inducer and away from anyone trying to help them.
No one knows what causes SDD exactly but stress and social isolation are the main contributors. When we are socially isolated the few people we do talk to become very important to us, and therefore they are seen as more trustworthy, so when an inducer is sharing their delusions, the second person is more likely to believe them. Additionally, since they are socially isolated, people developing shared delusional disorder do not have others reminding them that their delusions are either impossible or not likely, and are therefore more likely to develop SDD. In fact, the treatment for shared delusional disorder is for the person to be removed from the inducer and seek additional treatment, if necessary.
Stress is also a factor because it triggers mental illness. The majority of people that develop shared delusional disorder are genetically predisposed to mental illness; however this predisposition ( i.e. genes for schizophrenia that need to be activated) is not enough to develop a mental disorder. However, when that person becomes stressed their adrenal gland releases the stress hormone cortisol into the body which released increased levels of dopamine in their brain and changes in dopamine levels are linked to mental illness. As a result, stress puts one at a heightened risk of developing a psychological disorder such as shared delusional disorder.
Shared delusional disorder is hard to diagnose because usually, the afflicted person does not seek out treatment because they do not realize that their delusion is abnormal as it comes from someone in a dominant position who they trust. Furthermore, since their delusion comes on gradually and grows in strength over time, their doubt is slowly weakened during this time. Shared delusional disorder is diagnosed using the DSM-5 and according to this the person afflicted must meet three criteria:
- They must have a delusion that develops in the context of a close relationship with an individual with an already established delusion.
- The delusion must be very similar or even identical to the one already established one that the primary case has.
- The delusion cannot be better explained by any other psychological disorder, mood disorder with psychological features, a direct result of physiological effects of substance abuse or any general medical condition 
After a person has been diagnosed, the next step is to determine the proper course of treatment. The first step is to separate the formerly healthy person from the inducer and see if the delusion goes away or lessens over time. If this is not enough to stop the delusions there are two possible courses of action: Medication or therapy which is then broken down into personal therapy and/or family therapy.
- Medication: if the separation alone is not working, antipsychotics are often prescribed for a short time to prevent the delusions. Antipsychotics are medications that reduce or relieve symptoms of psychosis such as delusions or hallucinations (seeing or hearing something that is not there). Other uses of antipsychotics include stabilizing moods for people with mood swings and mood disorders ( i.e. in bipolar patients), reducing anxiety in anxiety disorders and lessening tics in people with Tourettes. Antipsychotics do not cure psychosis but they do help reduce the symptoms and when paired with therapy, the afflicted person has the best chance of recovering. While antipsychotics are powerful, and often effective, they do have side effects such as inducing involuntary movements and should only be taken if absolutely required and under the supervision of a psychiatrist.
- Therapy: the two most common forms of therapy for people suffering from shared delusional disorder are personal and family therapy. Personal therapy is one-on-one counseling that focuses on building a relationship between the counselor and the patient and aims to create a positive environment where the patient feels that they can speak freely and truthfully. This is advantageous because the counselor can usually get more information out of the patient to get a better idea of how to help them if that patient feels safe and trusts them. Additionally if the patient trusts what the counsellor says disproving the delusion will be easier.
Family therapy is a technique in which the entire family comes into therapy together to work on their relationships and to find ways to eliminate the delusion within the family dynamic. For example, if someone's sister is the inducer the family will have to get involved to ensure the two stay apart and to sort out how the family dynamic will work around that. The more support a patient has the more likely they are to recover, especially since SDD usually occurs because of social isolation.
With treatment, the delusions and therefore the disease will eventually lessen so much so that it will practically disappear in most cases. However left untreated it can become chronic and lead to anxiety, depression, aggressive behavior and further social isolation. Unfortunately there are not many statistics about the prognosis of shared delusional disorder as it is a rare disease and it is expected that the majority of cases go unreported; however, with treatment, the prognosis is very good.
Shared delusional disorder is most commonly found in women with slightly above-average IQs who are isolated from their family, and are in relationships with a dominant person who has delusions. The majority of secondary cases (people who develop the shared delusion) also meet the criteria for Dependent Personality Disorder which is characterized by a pervasive fear that leads them to need constant reassurance, support and guidance. Additionally, 55% of secondary cases had a relative with a psychological disorder that included delusions and, as a result, the secondary cases are usually susceptible to mental illness. The disorder can also occur in cults to a serious extent; one example is Heaven's Gate, a UFO religion led by Marshall Applewhite, who had delusions about extraterrestrial life. The members of the cult developed the same delusion, and went on to commit suicide with the intention of their spirits joining an extraterrestrial spacecraft heading towards a comet.
In May 2008, in the case of twin sisters Ursula and Sabina Eriksson, Ursula ran into the path of an oncoming articulated lorry, sustaining severe injuries. Sabina then immediately duplicated her twin's actions by stepping into the path of an oncoming car; both sisters survived the incident with severe but non-life-threatening injuries. It was later claimed that Sabina Eriksson was a 'secondary' sufferer of folie à deux, influenced by the presence or perceived presence of her twin sister, Ursula – the 'primary'. Sabina later told an officer at the police station, "We say in Sweden that an accident rarely comes alone. Usually at least one more follows – maybe two." However, upon her release from hospital, Sabina behaved erratically before stabbing a man to death.
The case of Ian Brady and Myra Hindley, Britain's notorious child killers in what became known as The Moor Murders, is another instance where folie à deux was said to occur. Hindley came, through her relationship with Brady to believe his racist philosophy that included a fascination with Hitler and fascism.
Another case involved Margaret and her husband Michael, both aged 34 years, who were discovered to be suffering from folie à deux when they were both found to be sharing similar persecutory delusions. They believed that certain persons were entering their house, spreading dust and fluff and "wearing down their shoes". Both had, in addition, other symptoms supporting a diagnosis of emotional contagion, which could be made independently in either case.
The psychiatrist Reginald Medlicott published an article about the Parker-Hulme murder case called “Paranoia of the Exalted Type in a Setting of Folie a Deux - A Study of Two Adolescent Homicides”, arguing that the intense relationship and shared fantasy world of the two teenaged friends reinforced and exacerbated the mental illness that led to the murder: “each acted on the other as a resonator increasing the pitch of their narcissism.”
In 2016, a case involving a family of five from Melbourne, Australia made headlines when they abruptly fled their home and travelled more than 1,600 km (1,000 mi) across the state of Victoria because some of the family had become convinced someone was out to kill and rob them. No such evidence was found by the police, and the symptoms of those involved resolved on their own once the family returned to their home.
The book Bad Blood: Secrets and Lies in a Silicon Valley Startup suggests that this ailment plagued the founder of Theranos, Elizabeth Holmes, and her boyfriend/business partner Ramesh Balwani.
- In 1998, the nineteenth episode in the fifth season of The X-Files was titled "Folie à Deux" and details a story of a man who believes his boss is an insect monster, a delusion that Fox Mulder begins to believe after investigation.
- The 2006 Lionsgate film Bug depicts a couple with a shared delusion that aphids are living under their skin.
- In 2006, in the show Criminal Minds (Season 2, Episode 3 "The Perfect Storm") it is mentioned by Dr. Reid that the rapists had this condition.
- In 2008, American rock band Fall Out Boy released their fourth album, Folie à Deux.
- The 2011 independent film Apart depicts two lovers affected and diagnosed with induced delusional disorder, trying to uncover a mysterious and tragic past they share. In a 2011 interview, director Aaron Rottinghaus stated the film was based on research from actual case studies.
- In March 2011, in the show CSI: Miami (Season 9, Episode 15 "Blood Lust"), it was revealed the killer couple had this condition.
- In April 2012, in the show Criminal Minds (Season 7, Episode 19 "Heathridge Manor"), it was revealed the killer family had this condition.
- In November 2017, in the show Chance (Season 2, Episode 9 "A Madness of Two"), it was revealed the villains are suffering from this condition.
- Anxiety disorder
- Delusional disorder
- Delusional parasitosis
- Emotional contagion
- Folie à Deux (album)
- Hive mind
- Hysterical contagion
- Major depressive disorder
- Mass hysteria
- Mass psychogenic illness
- Slender Man stabbing
- Wells, John C. (2008), Longman Pronunciation Dictionary (3rd ed.), Longman, p. 665, ISBN 9781405881180
- Berrios G E & Marková IS (2015) Shared Pathologies. In Bhugra D & Malhi G (eds) Troublesome disguises. Managing challenging Disorders in Psychiatry. 2nd Edition, London, Wiley, pp3-15
- Arnone D, Patel A, Tan GM (2006). "The nosological significance of Folie à Deux: a review of the literature". Annals of General Psychiatry. 5: 11. doi:10.1186/1744-859X-5-11. PMC 1559622. PMID 16895601.
- Dantendorfer K, Maierhofer D, Musalek M (1997). "Induced hallucinatory psychosis (folie à deux hallucinatoire): pathogenesis and nosological position". Psychopathology. 30 (6): 309–15. doi:10.1159/000285071. PMID 9444699.
- "Dr. Nigel Eastman in the BBC documentary 'Madness In The Fast Lane'". Documentarystorm.com. 2010-09-24. Archived from the original on 2010-10-01. Retrieved 2011-05-31.
- Berrios G E (1998) Folie à deux (by W W Ireland). Classic Text Nº 35. History of Psychiatry 9: 383–395
- Dewhurst, Kenneth; Todd, John (1956). "The psychosis of association: Folie à deux". Journal of Nervous and Mental Disease. 124 (5): 451–459. doi:10.1097/00005053-195611000-00003. PMID 13463598.
- "Shared Psychotic Disorder Symptoms - Psych Central". Psych Central. 2016-05-17. Retrieved 2018-03-22.
- "Delusional Disorder | Psychology Today". Psychology Today. Retrieved 2018-03-22.
- "Delusion Types". News-Medical.net. 2010-08-15. Retrieved 2018-03-22.
- "4 Types of Delusions & Extensive List of Themes - Mental Health Daily". Mental Health Daily. 2015-04-29. Retrieved 2018-03-22.
- "How stress affects your body and behavior". Mayo Clinic. Retrieved 2018-03-22.
- "Stress May Trigger Mental Illness and Depression In Teens". EverydayHealth.com. Retrieved 2018-03-22.
- "Anxiety: Causes, symptoms, and treatments". Medical News Today. Retrieved 2018-03-22.
- "Shared Psychotic Disorder - Treatment Options". luxury.rehabs.com. Retrieved 2018-03-22.
- "Symptoms of Shared Psychotic Disorder". www.mentalhelp.net. Retrieved 2018-03-22.
- "Incapacitating Agents". Brooksidepress.org. Retrieved 2011-05-31.
- "Medscape Access". Emedicine.com. Retrieved 2011-05-31.
- "CAMH: Antipsychotic Medication". www.camh.ca. Retrieved 2018-03-22.
- "Benefits of Individual Therapy | Therapy Groups". www.therapygroups.com. Retrieved 2018-03-22.
- "Teen Treatment Center Blog". Teen Treatment Center. Retrieved 2018-03-22.
- "Dependent Personality Disorder Symptoms - Psych Central". Psych Central. 2017-12-17. Retrieved 2018-03-22.
- "TV Review: Madness In The Fast Lane – BBC1". The Sentinel. 11 August 2010. Retrieved 31 August 2010.
- "TV Preview: Madness In The Fast Lane – BBC1, 10.35 pm". The Sentinel. 10 August 2010. Retrieved 31 August 2010.
- "Why was Sabina Eriksson free to kill?". The Sentinel. 3 September 2009. Retrieved 31 August 2010.
- Bamber, J (7 September 2009). "Could M6 film of killer have saved victim?". The Sentinel. Retrieved 31 August 2010.
- Madness In The Fast Lane Archived 2010-10-01 at the Wayback Machine Retrieved 3 February 2011.
- This case study is taken from Enoch and Ball's 'Uncommon Psychiatric Syndromes' (2001, p181)
- McCurdy, Marian Lea (2007). "Women Murder Women: Case Studies in Theatre and Film" (PDF).
- "Tromp family: The mystery of a tech-free road trip gone wrong - BBC News". BBC News. 2016-09-07. Retrieved 2016-09-07.
- PTI. "Burari deaths: Family may have been suffering from 'shared psychosis'". @businessline.
- "Burari deaths: Family could have been suffering from 'shared psychotic disorder', says Delhi Police". Hindustan Times. 3 July 2018.
- "Delhi Family Found Hanging Expected To Be Saved 'When Water Turns Blue'". NDTV.com.
- Wikipedia https://en.wikipedia.org/wiki/List_of_The_X-Files_episodes. Retrieved 21 March 2020. Missing or empty
- Cangialosi, Jason. "SXSW 2011: Interview with Aaron Rottinghaus, Director of 'Apart'". Yahoo!. Archived from the original on 29 April 2014. Retrieved 13 August 2013.
- Halgin, R. & Whitbourne, S. (2002) Abnormal Psychology: Clinical Perspectives on Psychological Disorders. McGraw-Hill. ISBN 0072817216
- Enoch, D. & Ball, H. (2001) Folie à deux (et Folie à plusieurs). In Enoch, D. & Ball, H. Uncommon psychiatric syndromes (Fourth edition). London: Arnold. ISBN 0340763884
- Ketchum, James S., M. D. Chemical Warfare: Secrets Almost Forgotten A Personal Story of Medical Testing of Army Volunteers. Chembook, Inc.; second 2007 edition (December 11, 2006)ISBN 1424300800; ISBN 978-1424300808
- Wehmeier PM, Barth N, Remschmidt H (2003). "Induced delusional disorder. a review of the concept and an unusual case of folie à famille". Psychopathology. 36 (1): 37–45. doi:10.1159/000069657. PMID 12679591.
- Hatfield, Elaine; Caccioppo, John T & Rapson, Richard L. (1994). Emotional contagion (Studies in Emotional and Social Interaction). Cambridge, UK: Cambridge University Press. ISBN 0-521-44948-0.
- Metzner, Ralph, ed. (1999-06-02). Ayahuasca: Human Consciousness and the Spirits of Nature. New York, NY: Thunder's Mouth Press. ISBN 1-56025-160-3.
- Folie à deux: Two case reports
- "Shared Psychotic Manic Syndrome in Monozygotic Twins".
- "Genetic of Psychogenic? A case study of "Folie a quarter" including twins"
- Shared Delusional Disorder in a Cult