Exoribonuclease II

Exoribonuclease II (EC 3.1.13.1, ribonuclease II, ribonuclease Q, BN ribonuclease, Escherichia coli exo-RNase II, RNase II, exoribonuclease (misleading), 5'-exoribonuclease) is an enzyme.[1][2][3][4] This enzyme catalyses the following chemical reaction

Exoribonuclease II
Identifiers
EC number3.1.13.1
CAS number37288-24-7
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Exonucleolytic cleavage in the 3'- to 5'-direction to yield nucleoside 5'-phosphates

This enzyme has preference for single-stranded RNA.

See alsoEdit

ReferencesEdit

  1. ^ Nossal NG, Singer MF (March 1968). "The processive degradation of individual polyribonucleotide chains. I. Escherichia coli ribonuclease II". The Journal of Biological Chemistry. 243 (5): 913–22. PMID 4867942.
  2. ^ Schmidt FJ, McClain WH (November 1978). "An Escherichia coli ribonuclease which removes an extra nucleotide from a biosynthetic intermediate of bacteriophage T4 proline transfer RNA". Nucleic Acids Research. 5 (11): 4129–39. doi:10.1093/nar/5.11.4129. PMC 342738. PMID 364422.
  3. ^ Shimura Y, Sakano H, Nagawa F (May 1978). "Specific ribonucleases involved in processing of tRNA precursors of Escherichia coli. Partial purification and some properties". European Journal of Biochemistry. 86 (1): 267–81. doi:10.1111/j.1432-1033.1978.tb12308.x. PMID 350582.
  4. ^ Sporn MB, Lazarus HM, Smith JM, Henderson WR (April 1969). "Studies on nuclear exoribonucleases. 3. Isolation and properties of the enzyme from normal and malignant tissues of the mouse". Biochemistry. 8 (4): 1698–706. doi:10.1021/bi00832a053. PMID 5805304.

External linksEdit