Open main menu

Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).

Etoxeridine
Etoxeridine.svg
Clinical data
SynonymsEtoxeridine, Carbetidine, Atenos
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.750 Edit this at Wikidata
Chemical and physical data
FormulaC18H27NO4
Molar mass321.417 g·mol−1
3D model (JSmol)
  (verify)

Etoxeridine was developed in the 1950s[1] and investigated for use in surgical anesthesia, however it was never commercialized and is not currently used in medicine.[2][3][4] As with other opioids which were not in clinical use during the drafting of the Controlled Substances Act, it is categorized as a Schedule I narcotic.

ReferencesEdit

  1. ^ BE 558883 
  2. ^ Merlevede E, Levis S. (1958). "Pharmacological study of carbetidine, a new synthetic analgesic". Archives Internationales de Pharmacodynamie et de Thérapie (in French). 115 (1–2): 213–232.
  3. ^ Sironi PG (1959). "Brief note on a new synthetic analgesic: carbetidine hydrochloride". Minerva Anestesiologica (in Italian). 25 (6): 251–254.
  4. ^ Crawford JS, Foldes FF (1959). "Studies on the respiratory and circulatory effects of carbetidine HCl used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia". British Journal of Anaesthesia. 31: 348–351.