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Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).

Clinical data
SynonymsEtoxeridine, Carbetidine, Atenos
ATC code
  • none
Legal status
Legal status
CAS Number
PubChem CID
CompTox Dashboard (EPA)
ECHA InfoCard100.006.750 Edit this at Wikidata
Chemical and physical data
Molar mass321.417 g·mol−1
3D model (JSmol)

Etoxeridine was developed in the 1950s[1] and investigated for use in surgical anesthesia, however it was never commercialized and is not currently used in medicine.[2][3][4] As with other opioids which were not in clinical use during the drafting of the Controlled Substances Act, it is categorized as a Schedule I narcotic.


  1. ^ BE 558883 
  2. ^ Merlevede E, Levis S. (1958). "Pharmacological study of carbetidine, a new synthetic analgesic". Archives Internationales de Pharmacodynamie et de Thérapie (in French). 115 (1–2): 213–232.
  3. ^ Sironi PG (1959). "Brief note on a new synthetic analgesic: carbetidine hydrochloride". Minerva Anestesiologica (in Italian). 25 (6): 251–254.
  4. ^ Crawford JS, Foldes FF (1959). "Studies on the respiratory and circulatory effects of carbetidine HCl used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia". British Journal of Anaesthesia. 31: 348–351.