Domingo Cordero Clase (born 17 October 1965 in Santo Domingo, Dominican Republic) is a retired Puerto Rican track and field athlete who specialized in the 400 metres hurdles. His personal best time was 49.12 seconds, achieved in July 1991 in Xalapa. This was the Puerto Rican record.
He won gold medals at the 1990 and 1993 Central American and Caribbean Games as well as the 1989 and 1991 Central American and Caribbean Championships. He won the bronze medal at the 1993 Central American and Caribbean Championships and the silver medal in 1995.