Open main menu

Wikipedia β

Diglyme, or bis(2-methoxyethyl) ether, is a solvent with a high boiling point. It is an organic compound which is the dimethyl ether of diethylene glycol. (The name "diglyme" is a portmanteau of "diglycol methyl ether.") It is a clear, colorless liquid with a slight ether-like odor. It is miscible with water, alcohols, diethyl ether, and hydrocarbon solvents. It is prepared by a reaction of dimethyl ether and ethylene oxide over an acid catalyst.[2]

Diglyme
Skeletal formula of diglyme
Space-filling model of the diglyme molecule
Names
Preferred IUPAC name
1-Methoxy-2-(2-methoxyethoxy)ethane[1]
Other names
Diglyme
2-Methoxyethyl ether
Di(2-methoxyethyl) ether
Diethylene glycol dimethyl ether
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
DrugBank
ECHA InfoCard 100.003.568
EC Number 203-924-4
UNII
Properties
C6H14O3
Molar mass 134.18 g·mol−1
Density 0.937 g/mL
Melting point −64 °C (−83 °F; 209 K)
Boiling point 162 °C (324 °F; 435 K)
miscible
Hazards
Toxic (T)
Flammable (F)
R-phrases (outdated) R60 R61 R10 R19
S-phrases (outdated) S53 S45
Flash point 57 °C (135 °F; 330 K)
Related compounds
Related compounds
Diethylene glycol diethyl ether, ethylene glycol dimethyl ether
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYNo ?)
Infobox references

SolventEdit

Its stability, even at high pH values, makes it an excellent solvent for reactions with strong bases or reactions that require high temperatures.

Diglyme is mainly used as a solvent. It serves as a chelate for alkali metal cations, leaving anions more active. Therefore, reactions involving organometallic reagents, such as Grignard reactions or metal hydride reductions, may have significantly enhanced reaction rates.[3] Diglyme is also used as a solvent in hydroboration reactions with diborane.

ReferencesEdit

  1. ^ Nomenclature of Organic Chemistry : IUPAC Recommendations and Preferred Names 2013 (Blue Book). Cambridge: The Royal Society of Chemistry. 2014. p. 704. doi:10.1039/9781849733069-FP001. ISBN 978-0-85404-182-4. 
  2. ^ Siegfried Rebsdat; Dieter Mayer (2005), "Ethylene Glycol", Ullmann's Encyclopedia of Industrial Chemistry, Weinheim: Wiley-VCH, doi:10.1002/14356007.a10_101 
  3. ^ J. E. Ellis, A. Davison (1976). "Tris[Bis(2-Methoxyethyl)Ether]Potassium and Tetraphenylarsonium Hexacarbonylmetallates(1–) of Niobium and Tantalum". Inorg. Synth. 16: 68–73. doi:10.1002/9780470132470.ch21.