|No. 11 – Indianapolis Colts|
|Born:||August 9, 1996|
|Height:||6 ft 2 in (1.88 m)|
|Weight:||202 lb (92 kg)|
|High school:||Tampa Bay Technical|
|NFL Draft:||2018 / Round: 6 / Pick: 185|
|Career highlights and awards|
|Career NFL statistics|
Cain attended Tampa Bay Technical High School in Tampa, Florida. He played quarterback for the high school football team. He was rated as a five-star recruit and committed to Clemson University to play college football under head coach Dabo Swinney.
Cain moved to wide receiver at Clemson. As a true freshman in 2015, he played in 13 games, recording 34 receptions for 582 yards and five touchdowns. He did not play in the 2015 Orange Bowl or 2016 College Football Playoff National Championship due to suspension for failing a drug test. Cain returned from the suspension in 2016, and played in all 15 games, including Clemson's 2017 College Football Playoff National Championship victory over Alabama. For the season, he had 38 receptions for 724 yards and nine touchdowns. After his junior season, Cain decided to forgo his senior year and declare for the 2018 NFL Draft.
Cain was drafted by the Indianapolis Colts in the sixth round (185th overall) of the 2018 NFL Draft. In the first preseason game, Cain suffered a torn ACL after a promising training camp, prematurely ending his rookie season. Cain was placed on injured reserve on August 12, 2018. He made his NFL debut in the Colts' 2019 season opener against the Los Angeles Chargers. In the 30–24 loss, he had two receptions for 35 yards.
- "Can anyone contain Tampa Bay Tech's Deon Cain?". Tampa Bay Times. Retrieved September 25, 2019.
- "National top-five wide receiver Deon Cain commits to Clemson". Independent Mail. Retrieved September 25, 2019.
- "Tampa Bay Tech's Deon Cain chooses Clemson". Tampa Bay Times. Archived from the original on June 5, 2015.
- Lentz, Zach. "'Time off' done, Deon Cain ready to be Tiger weapon again". The Times and Democrat. Retrieved September 25, 2019.
- "Deon Cain back with Clemson as a better person". The State. Archived from the original on March 29, 2018.
- Kussoy, Howie (January 8, 2017). "Deon Cain's Clemson nightmare has become a second chance". New York Post. Retrieved September 25, 2019.
- Brenner, Aaron. "Clemson WR Deon Cain's road to redemption ends back home in Tampa". Post and Courier. Retrieved September 25, 2019.
- "Deon Cain's hard lesson can pay off in his hometown". ESPN.com. January 7, 2017. Retrieved September 25, 2019.
- Hope, Dan. "Deon Cain working to be a leader for Clemson football". Independent Mail. Retrieved September 25, 2019.
- "Clemson wide receiver Deon Cain declaring for NFL draft". USA Today. January 10, 2018. Retrieved March 28, 2018.
- "Indianapolis Colts Steal WR Deon Cain with Pick 185 in NFL Draft". StampedeBlue.com. April 28, 2018. Retrieved June 16, 2018.
- Wesseling, Chris (August 10, 2018). "Colts lose promising rookie WR Deon Cain to torn ACL". NFL.com.
- "Roster Moves: Colts Sign WR Matt Hazel, RB Branden Oliver; Place WR Deon Cain On IR". Colts.com. August 12, 2018.
- "Indianapolis Colts at Los Angeles Chargers - September 8th, 2019". Pro-Football-Reference.com. Retrieved September 25, 2019.