Formerly, the regional border was initially created in 1508 after royal decree, to separate the colonial governorships of Castilla de Oro and Nueva Andalucía, using the River Atrato as the boundary between the two goverorships.
The current limit was regulated by the Victoria-Velez Treaty signed in Bogota on August 20, 1924 by the Foreign Ministers of Panama, Nicolas Victoria; and Colombia, Jorge Velez. This treaty is officially registered in the Register No. 814 of the Treaty League of Nations, on 17 August 1925. The border was made based on the same Colombian law of June 9, 1855.
- Berrio-Lemm, Vladimir. A short survey of public international law: Limits of Costa Rica and Panama. Page 47. Lottery # 420 Cultural Magazine. September–October 1998
- De Leon, Raquel Maria. Boundaries and Borders'. Panama. 1965.