Chronotherapy (treatment scheduling)

Chronotherapy, also called chronotherapeutics[1] or chronotherapeutic drug delivery,[2] refers to the coordination of therapeutic treatments with an individual's circadian or other rhythmic cycles. This may be done to maximize effectiveness of a specific treatment, minimize possible side effects, or both.[3][4]

Chronotherapy (treatment scheduling)
MeSHD019454

In the treatment of psychiatric conditions including bipolar depression,[5][6] a form of chronotherapy combining intermittent sleep deprivation and morning bright light has shown efficacy and relative tolerability in a number of controlled studies.[7][8][9]

See also edit

References edit

  1. ^ "Medical dictionary". Merriam-Webster. Retrieved 6 January 2017.
  2. ^ Sajan J (October 2009). "Chronotherapeutics and Chronotherapeutic Drug Delivery Systems". Tropical Journal of Pharmaceutical Research. 8 (5): 467–475. doi:10.4314/tjpr.v8i5.48091. hdl:1807/60412. ISSN 1596-5996. Retrieved 6 January 2017. ...drug availability is timed to match rhythms of disease in order to optimize therapeutic outcomes and minimize side effects.
  3. ^ Dolgin, Elie (1 May 2018). "How to ruin cancer's day". Knowable Magazine. doi:10.1146/knowable-050118-014201. Retrieved 8 August 2022.
  4. ^ Walton, Zandra E.; Altman, Brian J.; Brooks, Rebekah C.; Dang, Chi V. (4 March 2018). "Circadian Clock's Cancer Connections". Annual Review of Cancer Biology. 2 (1): 133–153. doi:10.1146/annurev-cancerbio-030617-050216. ISSN 2472-3428. S2CID 91120424. Retrieved 9 August 2022.
  5. ^ Benedetti F, Barbini B, Fulgosi MC, Colombo C, Dallaspezia S, Pontiggia A, Smeraldi E (December 2005). "Combined total sleep deprivation and light therapy in the treatment of drug-resistant bipolar depression: acute response and long-term remission rates". The Journal of Clinical Psychiatry. 66 (12): 1535–40. doi:10.4088/jcp.v66n1207. PMID 16401154.
  6. ^ Benedetti F, Riccaboni R, Locatelli C, Poletti S, Dallaspezia S, Colombo C (February 2014). "Rapid treatment response of suicidal symptoms to lithium, sleep deprivation, and light therapy (chronotherapeutics) in drug-resistant bipolar depression". The Journal of Clinical Psychiatry. 75 (2): 133–40. doi:10.4088/JCP.13m08455. PMID 24345382.
  7. ^ Benedetti F, Barbini B, Colombo C, Smeraldi E (December 2007). "Chronotherapeutics in a psychiatric ward". Sleep Medicine Reviews. 11 (6): 509–22. doi:10.1016/j.smrv.2007.06.004. PMID 17689120.
  8. ^ Benedetti F (December 2012). "Antidepressant chronotherapeutics for bipolar depression". Dialogues in Clinical Neuroscience. 14 (4): 401–11. doi:10.31887/DCNS.2012.14.4/fbenedetti. PMC 3553570. PMID 23393416.
  9. ^ Dallaspezia S, Suzuki M, Benedetti F (December 2015). "Chronobiological Therapy for Mood Disorders". Current Psychiatry Reports. 17 (12): 95. doi:10.1007/s11920-015-0633-6. PMID 26478195. S2CID 39961490.