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Captafol is a fungicide.[2] It is used to control almost all fungal diseases of plants except powdery mildews.[3] It is believed to be a human carcinogen, and production for use as a fungicide in the United States stopped in 1987. Its continued use from existing stocks was allowed, but in 1999 the Environmental Protection Agency banned its use on all crops except onions, potatoes, and tomatoes. In 2006 even these exceptions were disallowed, so currently its use on all crops is banned in the United States. Several other countries have followed suit since 2000, and as of 2010, no countries are known to allow the use of captafol on food crops.[4] Currently, the National Institute for Occupational Safety and Health established a recommended exposure limit of 0.1 mg/m3 for dermal exposures.[5]

IUPAC name
Other names
cis-Captafol; Merpafol; Crisfolatan; Sulfonimide; Sulpheimide; Arborseal; Captaspor; Mycodifol; Pillartan; Terrazol; Difolatan
3D model (JSmol)
ECHA InfoCard 100.017.604
Molar mass 349.05 g·mol−1
Appearance White, crystalline solid
Melting point 161 °C; 321 °F; 434 K [1]
Boiling point decomposes
Vapor pressure 0.000008 mmHg (20°C) [1]
Main hazards potential occupational carcinogen
Flash point noncombustible [1]
US health exposure limits (NIOSH):
PEL (Permissible)
REL (Recommended)
Ca TWA 0.1 mg/m3 [skin][1]
IDLH (Immediate danger)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Captafol was disclosed in US patent 3,178,447 (1965).[6] Its synergistic mixture with thiabendazol was described in US patent 4092422 (1978).[7]

International trade in captafol is regulated by the Rotterdam Convention.


  1. ^ a b c d e f g "NIOSH Pocket Guide to Chemical Hazards #0098". National Institute for Occupational Safety and Health (NIOSH).
  2. ^ Captafol at
  3. ^ Captafol from Extension Toxicology Network
  4. ^ Captafol CAS No. 2425-06-1 Reasonably anticipated to be a human carcinogen National Institute of Health, Report on Carcinogens, Twelfth Edition (2011)
  5. ^ NIOSH Pocket Guide to Chemical Hazards from Centers of Disease Control and Prevention
  6. ^ "N-polyhaloalkylthio compounds". 1965-04-13. US patent 3,178,447.. The term "captafol" is not used in this publication, but is described as disclosed in this patent in patent application 20080269051
  7. ^ "Synergistic fungicidal mixture of captafol and thiabendazol". US patent via PatentLens.

Further readingEdit

  • Captafol in the Pesticide Properties DataBase (PPDB)