CYP3A7 is an enzyme belonging to the cytochrome P450 family. It is 503 amino acids in size and shares 87% of its sequence with CYP3A4. It carries out a similar role in fetuses that CYP3A4 serves in adults. The gene location is 7q22.1.
|, CP37, CYPIIIA7, P-450(HFL33), P-450111A7, P450-HFLA, cytochrome P450 family 3 subfamily A member 7|
The CYP3A group of enzymes are the most abundantly expressed members of the cytochrome P450 family in liver. They are responsible for the metabolism of more than 50% of all clinical pharmaceuticals.
- GRCh38: Ensembl release 89: ENSG00000160870 - Ensembl, May 2017
- GRCm38: Ensembl release 89: ENSMUSG00000029727 - Ensembl, May 2017
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- CYP3A7*1C Allele Associated With Poor Outcomes in CLL, Breast, and Lung Cancer