CTRL (gene)

CTRL
Identifiers
Aliases	CTRL, CTRL1, chymotrypsin like
External IDs	OMIM: 118888 MGI: 88558 HomoloGene: 37549 GeneCards: CTRL
Gene location (Human)
Chr.	Chromosome 16 (human)
End	67,932,365 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	106,660,494 bp
RNA expression pattern
	Top expressed in
	body of pancreas; ; islet of Langerhans; ; blood; ; monocyte; ; bone marrow; ; spleen; ; bone marrow cells; ; lymph node; ; putamen; ; anterior pituitary;
	Top expressed in
	pyloric antrum; ; islet of Langerhans; ; duodenum; ; morula; ; Paneth cell; ; spleen; ; left lobe of liver; ; sexually immature organism; ; primitive streak; ; large intestine;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	peptidase activity; serine-type endopeptidase activity; hydrolase activity; serine-type peptidase activity;
Cellular component	extracellular space;
Biological process	proteolysis; protein catabolic process;
	Sources:Amigo / QuickGO
Orthologs
	1506
	109660
	ENSG00000141086
	ENSMUSG00000031896
	P40313
	Q9ER05
	NM_001907
	NM_023182
	NP_001898
	NP_075671
	Wikidata
View/Edit Human	View/Edit Mouse

Chymotrypsin-like protease CTRL-1 is an enzyme that in humans is encoded by the CTRL gene.^[5]^[6]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000141086 – Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031896 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Larsen F, Solheim J, Kristensen T, Kolsto AB, Prydz H (Feb 1994). "A tight cluster of five unrelated human genes on chromosome 16q22.1". Hum Mol Genet. 2 (10): 1589–95. doi:10.1093/hmg/2.10.1589. PMID 8268911.
^ "Entrez Gene: CTRL chymotrypsin-like".

External links edit

Human CTRL genome location and CTRL gene details page in the UCSC Genome Browser.

Further reading edit

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Heidtmann HH, Travis J (1994). "A novel chymotrypsin-like serine proteinase from human lung". Biol. Chem. Hoppe-Seyler. 374 (9): 871–5. doi:10.1515/bchm3.1993.374.7-12.871. PMID 8267879.
Mastroianni N, De Fusco M, Zollo M, et al. (1996). "Molecular cloning, expression pattern, and chromosomal localization of the human Na-Cl thiazide-sensitive cotransporter (SLC12A3)". Genomics. 35 (3): 486–93. doi:10.1006/geno.1996.0388. PMID 8812482.
Reseland JE, Larsen F, Solheim J, et al. (1997). "A novel human chymotrypsin-like digestive enzyme". J. Biol. Chem. 272 (12): 8099–104. doi:10.1074/jbc.272.12.8099. PMID 9065485.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Lee M, Calabresi L, Chiesa G, et al. (2002). "Mast cell chymase degrades apoE and apoA-II in apoA-I-knockout mouse plasma and reduces its ability to promote cellular cholesterol efflux". Arterioscler. Thromb. Vasc. Biol. 22 (9): 1475–81. doi:10.1161/01.ATV.0000029782.84357.68. PMID 12231569. S2CID 12259302.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000141086 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031896 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid8268911-5] Larsen F, Solheim J, Kristensen T, Kolsto AB, Prydz H (Feb 1994). "A tight cluster of five unrelated human genes on chromosome 16q22.1". Hum Mol Genet. 2 (10): 1589–95. doi:10.1093/hmg/2.10.1589. PMID 8268911.

[entrez-6] "Entrez Gene: CTRL chymotrypsin-like".

[5]

[6]

[1]

[2]

[3]

[4]