Blazein is a bio-active steroid made by Agaricus blazei.[1]

Blazein
Names
IUPAC name
(22E)-6β-Methoxy-5α-ergosta-7,22-diene-3β,5-diol
Systematic IUPAC name
(1R,3aR,5R,5aR,7S,9aR,9bS,11aR)-1-[(2R,3E,5R)-5,6-Dimethylhept-3-en-2-yl]-5-methoxy-9a,11a-dimethyl-1,2,3,3a,5,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-5aH-cyclopenta[a]phenanthrene-5a,7-diol
Identifiers
3D model (JSmol)
ChEBI
ChemSpider
  • InChI=1S/C29H48O3/c1-18(2)19(3)8-9-20(4)23-10-11-24-22-16-26(32-7)29(31)17-21(30)12-15-28(29,6)25(22)13-14-27(23,24)5/h8-9,16,18-21,23-26,30-31H,10-15,17H2,1-7H3/b9-8+/t19-,20+,21-,23+,24-,25-,26+,27+,28+,29-/m0/s1
    Key: GQVCGTRDXSDAHC-KNXFMRPFSA-N
  • CO[C@@H]1C=C2[C@H](CC[C@@]3(C)[C@H]2CC[C@@H]3[C@H](C)/C=C/[C@H](C)C(C)C)[C@@]2(C)CC[C@H](O)C[C@]12O
Properties
C29H48O3
Molar mass 444.690
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

References edit

  1. ^ Itoh, H; Ito, H; Hibasami, H (December 2008). "Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells". Oncol. Rep. 20 (6): 1359–61. doi:10.3892/or_00000152. PMID 19020714.