bioRxiv (pronounced "bio-archive") is a preprint repository for the biological sciences co-founded by John Inglis and Richard Sever in November 2013. It is hosted by the Cold Spring Harbor Laboratory (CSHL). As preprints, papers hosted on bioRxiv are not peer-reviewed, but undergo basic screening and checked against plagiarism. Readers may offer comments on the preprint. It was inspired by and intends to complement the arXiv repository, which mostly focuses on physics and connected disciplines, launched in 1991 by Paul Ginsparg (who also serves on the bioRxiv advisory board). It received support from both the CSHL and the Lourie Foundation. Additional funding from the Chan Zuckerberg Initiative was confirmed in April 2017.
Type of site
|Owner||Cold Spring Harbor Laboratory|
|Alexa rank||31,553 (as of July 2017)|
Prior to the establishment of bioRxiv, biological scientists were divided on the issue of having a dedicated preprint repository. Many had concerns of having their research scooped by competitors and losing their claim to discovery. However, several geneticists had submitted papers to the "quantitative biology" section of the arXiv repository (launched in 2003) and no longer had those concerns, as they could point to preprints to support their claims of discovery.
As a result of bioRxiv's popularity, several biology journals have updated their policies on preprints, clarifying they do not consider preprints to be a 'prior publication' for purpose of the Ingelfinger rule. Over 20,000 tweets were made about bioRxiv-hosted preprints in 2015. In July 2017, the number of monthly submissions exceeded 1,000.
Jocelyn Kaiser of Science said that in their first year, the repository had "attracted a modest but growing stream of papers", having hosted 824 preprints. As of February 2016, the submission rate to bioRxiv had steadily increased from ~60 to ~200 per month, with a total of 3100 papers received. As of April 21, 2017, >10,000 papers have been accepted in total. In 2017, the number of monthly submissions was more than 810 in March  and more than 1000 in July. By March 2018, this increased to just under 1,500.
bioRxiv accepts preprints in the following disciplines
- Animal behavior and cognition
- Cancer biology
- Cell biology
- Clinical trials
- Developmental biology
- Evolutionary biology
- Molecular biology
- Pharmacology and Toxicology
- Plant biology
- Scientific communication and education
- Synthetic biology
- Systems biology
bioRxiv to JournalsEdit
The bioRxiv to Journals (B2J) initiative allows authors to submit their manuscript directly to a journal's submission system through bioRxiv. Journals currently participating in B2J are:
- Acta Crystallographica Section D: Structural Biology
- American Journal of Human Genetics
- Antimicrobial Agents and Chemotherapy
- Applied and Environmental Microbiology
- Biochemical Journal
- Biology Open
- Biophysical Journal
- Bioscience Reports
- BMC Bioinformatics
- BMC Biology
- BMC Cancer
- BMC Ecology
- BMC Evolutionary Biology
- BMC Genetics
- BMC Microbiology
- BMC Neuroscience
- BMC Plant Biology
- BMC Veterinary Research
- BMC Zoology
- BMJ Open Science
- Brain Research
- Brain Topography
- Bulletin of Mathematical Biology
- Cell Reports
- Clinical and Vaccine Immunology
- Clinical Science
- Developmental Biology
- Disease Models & Mechanisms
- Drug Metabolism and Disposition
- The EMBO Journal
- EMBO Molecular Medicine
- EMBO Reports
- Environmental Health Perspectives
- Experimental Brain Research
- The FASEB Journal
- G3: Genes, Genomes, Genetics
- Genome Announcements
- Genome Biology
- Genome Research
- Genome Biology
- Hormones and Cancer
- Infection and Immunity
- Invertebrate Neuroscience
- Journal of Bacteriology
- Journal of Biological Chemistry
- The Journal of Cell Biology
- Journal of Cell Science
- The Journal of Clinical Endocrinology & Metabolism
- Journal of Clinical Investigation
- Journal of Clinical Microbiology
- Journal of the Endocrine Society
- Journal of Experimental Biology
- Journal of Experimental Botany
- The Journal of Experimental Medicine
- The Journal of General Physiology
- Journal of General Virology
- The Journal of Immunology
- Journal of Lipid Research
- Journal of Mammary Gland Biology and Neoplasia
- Journal of Medical Microbiology
- Journal of Molecular Evolution
- Journal of Neurophysiology
- The Journal of Neuroscience
- Journal of Pharmacology and Experimental Therapeutics
- Journal of Virology
- Learning & Memory
- Life Science Alliance
- Mechanisms of Development
- Medicinal Chemistry Research
- Microbial Genomics
- Molecular and Cellular Biology
- Molecular & Cellular Proteomics
- Molecular Biology of the Cell
- Molecular Pharmacology
- Molecular Systems Biology
- Molecular Vision
- Neuronal Signaling
- Neuroscience Letters
- Pharmaceutical Research
- Photosynthesis Research
- The Plant Cell
- Plant Cell, Tissue and Organ Culture
- Plant Direct
- Plant Molecular Biology
- Plant Physiology
- PLOS Computational Biology
- PLOS Genetics
- PLOS Medicine
- PLOS Neglected Tropical Diseases
- PLOS One
- PLOS Pathogens
- Science Advances
- Science Immunology
- Science Signaling
- Science Translational Medicine
- Stem Cell Research
- Theoretical Applied Genetics
- "biorxiv.org Site Overview". Alexa Internet. Retrieved 2017-07-20.
- "Advancing the sharing of research results for the life sciences". bioRxiv. Retrieved 2018-03-17.
- Callaway, Ewen (12 November 2013). "Preprints come to life". Nature. 503 (7475): 180. doi: .
- Cold Spring Harbor Laboratory. "bioRxiv preprints can now be submitted directly to leading research journals". PhysOrg. Retrieved 2018-03-17.
- "About bioRxiv". bioRxiv. Cold Spring Harbor Laboratory. Retrieved 2016-09-07.
- Inglis, John R.; Sever, Richard (12 February 2016). "bioRxiv: a progress report". ASAPbio. Retrieved 2016-09-11.
- Callaway, Ewen. "BioRxiv preprint server gets cash boost from Chan Zuckerberg Initiative". Nature. doi:10.1038/nature.2017.21894.
- Kaiser, Jocelyn (26 April 2017). "BioRxiv preprint server gets funding from Chan Zuckerberg Initiative". Science. doi:10.1126/science.aal1117.
- Callaway, Ewen (31 July 2012). "Geneticists eye the potential of arXiv". Nature. 488 (7409): 19. doi: . PMID 22859182.
- Kaiser, Jocelyn (11 November 2014). "BioRxiv at 1 year: A promising start". Science. Retrieved 2016-09-07.
- Inglis, John (2017-06-30). "A life sci #preprint milestone: @biorxivpreprint's first >1000 ms month. Thanks to authors, affiliates, and staff for making it happen". @JohnRInglis. Retrieved 2017-07-02.
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- "Richard Sever on Twitter". Twitter. Retrieved 2018-04-02.
- Jansen, Jaclyn (12 November 2013). "CSHL launches bioRxiv, a freely accessible, citable preprint server for biology". Cold Spring Harbor Laboratory. Retrieved 2016-09-11.
- Kaiser, Jocelyn (12 November 2013). "New Preprint Server Aims to Be Biologists' Answer to Physicists' arXiv". Science. Retrieved 2016-10-30.
- "BioRxiv preprint server launched". UC Berkeley Library News. 15 November 2013. Retrieved 2016-09-11.
- Callaway, Ewen; Powell, Kendall (16 February 2016). "Biologists urged to hug a preprint". Nature. 530 (7590): 265–265. doi:10.1038/530265a.
- Inglis, John (22 September 2016). "The bioRxiv preprint service" (PDF). COASP 2016.