Ann Clarke (immunologist)

Ann G. Clarke (née Jewkes) is a British immunologist and co-founder of the Frozen Ark project.[1]


Clarke's research focused on the immunological relationship between mouse mothers and embryos. For six years she was an Inspector for the Human Fertilisation and Embryology Authority.[1]

She and her husband Bryan Clarke made several scientific expeditions to French Polynesia, where they realised that the partula snail was facing rapid extinction after the introduction of a predator as a biological control for a different species. Inspired by this, they and Anne McLaren (1927-2007) founded the Frozen Ark project to preserve the DNA of species threatened with extinction. As of 2017 the project held some 48,000 frozen samples from 5,500 species.[2]

In 2017 Clarke was the subject of an episode of BBC Radio 4's The Life Scientific.[2]

Selected publicationsEdit

  • MacKenzie-Dodds, Jacqueline; Clarke, Ann; et al. (June 2013). "Recent Initiatives in Biodiversity Biobanking: Summary of Presentations from the ESBB 2012 Conference". Biopreservation and Biobanking. 11 (3): 182–188. doi:10.1089/bio.2013.0018. PMID 24850096.
  • Lerman, Dominik; Blomeke, Brunhilde; Browne, Robert; Clarke, Ann; et al. (March 2009). "Cryobanking of viable biomaterials: implementation of new strategies for conservation purposes". Molecular Ecology. 18 (6): 1030–1033. doi:10.1111/j.1365-294X.2008.04062.x. PMID 19207252.
  • Clarke, A. G. (January 2009). "The Frozen Ark Project: the role of zoos and aquariums in preserving the genetic material of threatened animals". International Zoo Yearbook. 43 (1): 222–230. doi:10.1111/j.1748-1090.2008.00074.x.
  • Hetherington, C. M.; Humber, D. P.; Clarke, Ann G. (August 1976). "Genetic and immunological aspects of litter size in the mouse". European Journal of Immunogenetics. 3 (4): 245–252. doi:10.1111/j.1744-313X.1976.tb00581.x. PMID 789780.
  • Clarke, Ann G.; Hetherington, C. M. (April 1972). "Immunogenetic aspects of maternal-fetal relations". Journal of Reproduction and Fertility. Supplement. 15: 99–118. PMID 4565753.
  • Clarke, Ann G.; Hetherington, C. M. (March 1971). "Effects of Maternal Preimmunization on the Decidual Cell Reaction in Mice". Nature. 230 (5289): 114–115. doi:10.1038/230114a0. PMID 4927009.

Personal lifeEdit

Ann Jewkes married Professor Bryan Clarke (1932-2014) in 1960. They had a daughter and a son.[3]


  1. ^ a b "Dr Ann Clarke". People. The Frozen Ark project. 2018-09-04. Retrieved 10 February 2020.
  2. ^ a b "Ann Clarke on The Frozen Ark". The Life Scientific. BBC Radio 4. 2017. Retrieved 10 February 2020.
  3. ^ "Professor Bryan Clarke - obituary". The Telegraph. 2014-03-05. Retrieved 10 February 2020.